protein 1,288 words KG: LDLRECEPTOR 2026-03-24
kind:proteinsection:proteinsstate:published
Contents

LDL Receptor Protein

🔬 Protein Info
Gene SymbolLDL-RECEPTOR
Full NameLDL Receptor
AliasesLDLRECEPTOR
Protein TypeProtein
FunctionThe LDL Receptor (LDLR) is a cell surface receptor essential for cholesterol homeostasis
Amino Acids40 aa
UniProt IDSearch UniProt
GeneCardsLDL-RECEPTOR
Human Protein AtlasLDL-RECEPTOR
Associated DiseasesAlzheimer'S Disease, disease
InteractionsLDLR, GPR146
KG Connections29 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (18)

Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.59
Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.57
APOE4 Allosteric Rescue via Small Molecule Chaperones
Score: 0.54
Circadian-Synchronized LRP1 Pathway Activation
Score: 0.53
Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides
Score: 0.51

Related Analyses (10)

Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived

Related Experiments (3)

Myricanol treatment in HFD-induced hyperlipidemic C57BL/6J m
validation · proposed · Score: 0.95
ox-LDL treatment of RAW264.7 macrophages
exploratory · proposed · Score: 0.85
Validation of hub genes in ox-LDL treated RAW264.7 macrophag
exploratory · proposed · Score: 0.80

See Also (15)

Senescent Cell Clearance in Neurodegeneration
mechanism · Pages share 6 hypotheses
RNA-Targeted Therapies in Neurodegeneration
mechanism · Pages share 6 hypotheses
PPAR Signaling Pathway in Neurodegeneration
mechanism · Pages share 6 hypotheses
Neurovascular Unit Dysfunction in Neurodegeneration
mechanism · Pages share 6 hypotheses
Endosomal Sorting Defects in Neurodegeneration
mechanism · Pages share 6 hypotheses