| Gene Symbol | MAP3K7 |
| Full Name | Mitogen-Activated Protein Kinase Kinase Kinase 7 |
| Aliases | MAP3K7PROTEIN |
| Chromosome | 6q15 |
| Protein Family | MAP3K family, STE20-like kinases |
| Function | MAP3K7 encodes TAK1 (Transforming Growth Factor Beta-Activated Kinase 1), a serine/threonine kinase that serves as a central mediator of inflammatory, stress-activated, and developmental signaling pat |
| Primary Expression | Ubiquitous (brain, immune, periphery) |
| Molecular Weight | 67 kDa |
| Amino Acids | 606 aa |
| Pathways | TGF-β, NF-κB |
| UniProt ID | [O43318](https://www.uniprot.org/uniprot/O43318) |
| Ensembl ID | ENSG00000171081 |
| OMIM | 602614 |
| GeneCards | MAP3K7 |
| Human Protein Atlas | MAP3K7 |
| Associated Diseases | neurodegeneration |
| Interactions | TLR4, RELA, TAK1, IKBKB, IL6, LC3 |
| KG Connections | 75 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |