| Gene Symbol | PCNA |
| Aliases | Proliferating Cell Nuclear Antigen |
| Protein Family | PCNA family, DNA clamp proteins |
| Function | Beyond its canonical roles in DNA replication, PCNA has been implicated in various neurodegenerative diseases, particularly those involving DNA repair dysfunction and replicative stress. |
| Subcellular Localization | Nucleus |
| Molecular Weight | 28.8 kDa |
| UniProt ID | P12004 |
| GeneCards | PCNA |
| Human Protein Atlas | PCNA |
| Gene | PCNA |
| Structure | Homotrimeric ring (PDB: 1AXC) |
| Disease Relevance | Alzheimer's Disease, Parkinson's Disease, Cancer, DNA Repair Disorders |
| Associated Diseases | ALS |
| Known Drugs/Compounds | rapamycin |
| Interactions | PI3K, PIK3CA, PSMA1, PSMB5, RPS6KB1, SMAD |
| KG Connections | 74 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |