| Gene Symbol | RBPJ |
| Full Name | RBPJ |
| Chromosome | 4q25 |
| Protein Type | Transcription Factor |
| Function | is a critical transcription factor that serves as the primary mediator of Notch signaling. |
| Primary Expression | cortical layers II-VI, particularly in layer 2/3 pyramidal neurons |
| Amino Acids | 434 aa |
| Pathways | Notch signaling, Notch, Notch Signaling, NOTCH |
| UniProt ID | [Q06323](https://www.uniprot.org/uniprot/Q06323) |
| Ensembl ID | ENSG00000168214 |
| GeneCards | RBPJ |
| Human Protein Atlas | RBPJ |
| Associated Diseases | neurodegeneration |
| Interactions | USP5, RNA, AKT1, NOTCH1, UBIQUITIN, VEGF |
| KG Connections | 34 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |