protein 617 words KG: RYR3 2026-03-22
kind:proteinsection:proteinsstate:published
Contents

Ryanodine Receptor 3 Protein

🔬 Protein Info
Gene SymbolRYR3
Full NameRyanodine Receptor 3
AliasesPage for RYR3
Chromosome15q13.3
Protein FamilyRyanodine receptor family
Protein TypeReceptor
FunctionRYR3 is the third ryanodine receptor isoform with widespread but lower expression than RYR1/RYR2.
Primary Expressionnumerous tissues including skeletal muscle, brain, heart, and other organs
Molecular Weight560 kDa
Amino Acids870 aa
UniProt IDQ15413
NCBI Gene ID6263
Ensembl IDENSG00000198853
GeneCardsRYR3
Human Protein AtlasRYR3
Associated DiseasesCardiac
KG Connections5 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (5)

Circadian Glymphatic Entrainment via Targeted Orexin Recepto
Score: 0.62
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51
Magnetosonic-Triggered Transferrin Receptor Clustering
Score: 0.47
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.42
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.35

Related Analyses (9)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived

See Also (6)

Packard Center for ALS Research
institution · KG edge: expressed_in
RYR2 - Ryanodine Receptor 2
gene · KG edge: associated_with
RYR1 - Ryanodine Receptor 1
gene · KG edge: associated_with
CAT — Catalase
gene · KG edge: expressed_in
Neurodegeneration
disease · KG edge: implicated_in

Knowledge Graph (5 edges)

RYR3 expressed_in Als
RYR3 associated_with Cardiac
RYR2 associated_with RYR3
CAT expressed_in RYR3
RYR1 associated_with RYR3