protein 625 words KG: SCARB1PROTEIN 2026-03-21
kind:proteinsection:proteinsstate:published
Contents

SCARB1 Protein (Scavenger Receptor Class B Type 1)

🔬 Protein Info
Gene SymbolSCARB1
AliasesScavenger Receptor Class B Type 1
Chromosome12q24.31
FunctionScavenger Receptor Class B Type 1 (SCARB1, also known as SR-BI) is a member of the scavenger receptor family that mediates selective uptake of cholesterol from HDL and other lipoproteins.
Molecular Weight82 kDa
Amino Acids509 aa
PathwaysCholesterol
GeneCardsSCARB1
Human Protein AtlasSCARB1
InteractionsTFEB, ABCA1
KG Connections11 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (18)

Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides
Score: 0.51
Circadian Glymphatic Entrainment via Targeted Orexin Recepto
Score: 0.62
APOE-Dependent Autophagy Restoration
Score: 0.61
Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.59
Competitive APOE4 Domain Stabilization Peptides
Score: 0.56

Related Analyses (9)

Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

Related Experiments (2)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40
Spinocerebellar Ataxia (SCA) Disease-Modifying Therapy Devel
validation · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in