| Gene Symbol | SCN2APROTEIN |
| Protein Type | Channel |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Primary Expression | excitatory neurons during early development and in specific brain regions throughout life |
| GeneCards | SCN2APROTEIN |
| Human Protein Atlas | SCN2APROTEIN |
| Brain Region | Expression Level |
| Cerebral [Cortex](/brain-regions/cortex) | High (Layer 2/3 pyramidal neurons) |
| [Hippocampus](/brain-regions/hippocampus) | Moderate (CA1-CA3 pyramidal cells) |
| Cerebellum | Low-Moderate |
| Thalamus | Moderate |
| Brainstem | Variable |
| Ankyrin-G | Structural |
| Beta subunits (SCN1B) | Modulatory |
| Calmodulin | Modulatory |
| Associated Diseases | Ataxia, Ms, Parkinson, autism spectrum disorder |
| KG Connections | 36 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |