| Gene Symbol | SLC1A3 |
| Full Name | Solute Carrier Family 1 Member 3 |
| Chromosome | 5p13.2 |
| Protein Type | Transporter |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Primary Expression | astrocytes and plays a critical role in maintaining extracellular glutamate homeostasis in the central nervous system by clearing glutamate from the s |
| Molecular Weight | 59 kDa |
| Pathways | climbing fiber innervation, glutamate clearance, glutamate transport, synaptic wrapping |
| UniProt ID | P43003 |
| NCBI Gene ID | 6507 |
| Ensembl ID | ENSG00000081189 |
| OMIM | 600116 |
| GeneCards | SLC1A3 |
| Human Protein Atlas | SLC1A3 |
| Glutamate clearance | Prevents excitotoxicity |
| Associated Diseases | Als, Alzheimer's disease, auditory function, spinocerebellar ataxia |
| Known Drugs/Compounds | arundic acid |
| Interactions | ALS, ALZHEIMER, ALZHEIMER'S DISEASE, APP, APP/PS1, ASC |
| KG Connections | 64 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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