protein 594 words KG: STAT4PROTEIN 2026-03-22
kind:proteinsection:proteinsstate:published
Contents

Signal Transducer and Activator of Transcription 4

🔬 Protein Info
Gene SymbolSTAT4PROTEIN
Chromosome2q32.3.
Protein FamilySTAT family transcription factors
Protein TypeTranscription Factor
FunctionSignal Transducer and Activator of Transcription 4 is a STAT family member. The protein contains the characteristic domain structure including domain descriptions.
Subcellular LocalizationCytoplasm, nucleus
Molecular Weight84 kDa
UniProt IDQ14765
GeneCardsSTAT4PROTEIN
Human Protein AtlasSTAT4PROTEIN
Protein NameSignal Transducer and Activator of Transcription 4
GeneSTAT4
PDB IDs3C54, 4B7Z, 5O0R
Associated Diseasesneurodegeneration
InteractionsIL6, TLR4, GSH, FERROPTOSIS, TIMP1, PDGFRB
KG Connections66 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (8)

Programmable Neuronal Circuit Repair via Epigenetic CRISPR
Score: 0.42
Purinergic Signaling Polarization Control
Score: 0.55
Mechanosensitive Ion Channel Reprogramming
Score: 0.51
Lipid Droplet Dynamics as Phenotype Switches
Score: 0.46
Vagal Afferent Microbial Signal Modulation
Score: 0.52

Related Analyses (9)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
CRISPR-based therapeutic approaches for neurodegenerative di
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived

Related Experiments (2)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40
Cytochrome Therapeutics
clinical · proposed · Score: 0.40

See Also (15)

Neurodegeneration
disease · KG edge: implicated_in
OSK Reprogramming and Yamanaka Factors in Neurodegenera
mechanism · Pages share 4 hypotheses
ALS Therapeutic Landscape — Programs by Phase and Modal
disease · Pages share 3 hypotheses
Wnt/β-Catenin Signaling Pathway in Neurodegeneration
mechanism · Pages share 3 hypotheses
WNK1-Bilirubin Signaling in Neuroinflammation and Neuro
mechanism · Pages share 3 hypotheses