| Gene Symbol | TWNK |
| Full Name | Twinkle mtDNA Helicase |
| Chromosome | 10q24.31 |
| Function | TWNK is a mitochondrial DNA helicase that unwinds double-stranded mtDNA during replication. |
| Subcellular Localization | ** | Mitochondrial nucleoid | |
| Pathways | Autophagy, Mitophagy |
| UniProt ID | Q9NYV5 |
| NCBI Gene ID | 56652 |
| Ensembl ID | ENSG00000107815 |
| OMIM | 604367 |
| GeneCards | TWNK |
| Human Protein Atlas | TWNK |
| mtDNA copy number | Twinkle levels regulate mtDNA copy number per mitochondrion |
| Nucleoid organization | Twinkle is a core component of the mitochondrial nucleoid |
| mtDNA repair | May participate in mtDNA damage bypass or repair processes |
| Associated Diseases | neurodegeneration |
| Interactions | AND, MTDNA |
| KG Connections | 10 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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