protein 633 words KG: XRCC3PROTEIN 2026-03-21
kind:proteinsection:proteinsstate:published
Contents

XRCC3 Protein

🔬 Protein Info
Gene SymbolXRCC3
Full NameX-Ray Repair Cross Complementing 3
AliasesXRCC3PROTEIN
Chromosome14q32.33
FunctionXRCC3 functions primarily in the homologous recombination pathway of DNA double-strand break (DSB) repair:
Molecular Weight38 kDa
PathwaysApoptosis, Invasion
UniProt ID[Q9UQE5](https://www.uniprot.org/uniprot/Q9UQE5)
Ensembl IDENSG00000113147
OMIM600675
GeneCardsXRCC3
Human Protein AtlasXRCC3
Associated DiseasesTumor
InteractionsBAX, DNA, P53, APOPTOSIS, CANCER
KG Connections16 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (4)

SASP-Mediated Complement Cascade Amplification
Score: 0.70
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.42
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.35

Related Analyses (7)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

Related Experiments (7)

Proposed experiment from debate on Synaptic pruning by micro
falsification · proposed · Score: 0.46
Proposed experiment from debate on Senolytics targeting p16/
falsification · proposed · Score: 0.46
Mechanism: Why Does Amyloid Removal Only Slow Decline 27%?
clinical · proposed · Score: 0.46
Experiment: Autoimmune Hypothesis Testing in AD
clinical · proposed · Score: 0.46
Mixed Pathology Effects on Parkinson's Disease Progression a
clinical · proposed · Score: 0.46

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in