gene 1,286 words KG: SMN2 2026-03-24
kind:genesection:genesstate:published
Contents

SMN2 Gene

🧬 Gene Info
Gene SymbolSMN2
Full NameSurvival of Motor Neuron 2, Telomeric
Chromosome5q13.2.
FunctionThe SMN complex plays a critical role in pre-mRNA splicing by facilitating the biogenesis of U1, U2, U4, and U5 snRNPs[@pellizzoni2002].
Molecular Weight~32 kDa
Amino Acids294 aa
UniProt IDQ16637
NCBI Gene ID6609
Ensembl IDENSG00000120247
OMIM601627
GeneCardsSMN2
Human Protein AtlasSMN2
Protein NameSurvival of Motor Neuron protein
Protein Length294 amino acids
TissueExpression Level
Associated DiseasesALS
InteractionsSMN1, Rb, NEURON, MOTOR NEURONS, AND
KG Connections23 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Knowledge Graph (12 edges)

SMN2 expressed_in SMN1
SMN2 therapeutic_target Mrna Processing
SMN2 interacts_with SMN1
SMN2 interacts_with Spinal Muscular Atrophy
SMN2 interacts_with Rb
SMN2 therapeutic_target MOTOR NEURONS
SMN2 therapeutic_target NEURON
SMN2 interacts_with NEURON
SMN2 associated_with RNA
SMN2 associated_with Als

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