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cell 1,834 words KG: stress
Contents

Stress Granule Formation in Neurodegeneration

🧫 Cell Type Info
Cell Typestress
Related GenesERK, MMP9
Linked Hypotheses3 hypotheses

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Knowledge Graph

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🌐 Cross-references

Wikipedia

Related Hypotheses (18)

eIF2α Phosphorylation Imbalance Creates Integrated Stress Re
Score: 0.90ATM Kinase Hyperactivation Triggers DNA Damage Response Over
Score: 0.84TIA1 Low-Complexity Domain Oxidation Drives Aberrant Stress
Score: 0.81GRN/progranulin lysosomal insufficiency across FTD, ALS-spec
Score: 0.76A downstream LRRK2-Rab10-JIP4 lysosomal stress loop promotes
Score: 0.68Rab12 may better report chronic lysosomal stress biology tha
Score: 0.67Amyloid-beta induces secondary pericyte senescence after con
Score: 0.64mutant FUS effects split between motor-neuron intrinsic stre
Score: 0.63ATF4-DDIT3 stress signaling indirectly represses MAPT transc
Score: 0.62A genetically encoded reporter for axonal mitochondrial prot
Score: 0.57SIRT3 loss creates a mitochondrial acetylation-stress loop t
Score: 0.56BBB leak induces secondary pericyte senescence through TGF-b
Score: 0.56NRF2 pathway activation to reduce mutant huntingtin aggregat
Score: 0.54REST-like neuronal silencing programs suppress MAPT in sever
Score: 0.51Reactive astrocyte glutamate-handling failure sustains dendr
Score: 0.49Astrocyte-specific autophagy deficiency induces NADPH oxidas
Score: 0.39XOR+ stress-responsive astrocytes represent a novel AD-assoc
Score: 0.38Tissue-Specific Stress Response Pathway Enhancement
Score: 0.00

Knowledge Graph (12 edges)

locus coeruleus regulates stress
stress activates MMP9
stress modulates microbiota-gut-brain axis
stress risk_factor_for depression
stress associated_with pulse rate
32250301 are not mediated by stress
stress triggers senescence
stress activates ERK
neuroinflammation associated_with stress
stress increases_risk mitochondrial_dysfunction

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