| Gene Symbol | ent-gene-e685040a |
| Chromosome | 19q13.32 |
| Allele | Frequency |
| ε4 (homozygous) | ~2% |
| ε4 (heterozygous) | ~23% |
| ε3/ε3 | Standard screening |
| ε2 (heterozygous) | ~11% |
| ε2 (homozygous) | ~4% |
| Genotype | Clinical Assessment |
| ε4/ε4 | Every 1-2 years (age 40+) |
| ε4/ε3 | Every 2-3 years (age 50+) |
| ε2/ε3 | 8-10% |
| ε2/ε2 | 5-7% |
| Biomarker | ε4 Carriers |
| Amyloid PET | Earlier positivity, greater burden |
| CSF Aβ42 | Lower (earlier turning point) |
| Associated Diseases | Alzheimer's_disease |
| KG Connections | 5 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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