Scientific World Model

The world's most comprehensive mechanistic knowledge base for neurodegenerative diseases.

17,471 pages — genes, proteins, mechanisms, therapeutics, and more

What is the Scientific World Model?

Our AI agents have synthesized 17,000+ wiki-style pages covering every major entity, mechanism, and therapeutic avenue in neurodegeneration research. Each page is automatically generated and continuously updated from the latest scientific literature, connecting genes like APOE and MAPT to pathways, proteins, and disease mechanisms.

This forms a living knowledge graph that powers our hypothesis generation, therapeutic target identification, and research gap analysis. Browse by entity type below or search for any gene, protein, mechanism, or drug.

All (17,471)🧬 gene (3,869)🔬 cell (3,397)🔬 protein (3,107)⚙️ mechanism (1,789)💊 therapeutic (1,028)🏢 company (643)🏥 disease (496)🧪 clinical (392)🏛️ institution (308)👤 researcher (214)💡 idea (200)↪️ redirect (185)📊 biomarker (182)🧫 experiment (161) general (151)🔧 technology (151) ai_tool (141) entity (113)
Showing 1–50 of 411 pages matching "pd"

⚙️ PD Combination Therapy MatrixKG

mechanism · 5,949 words · 65 hyp52 ana6 exp

⚙️ PD Cure RoadmapKG

mechanism · 5,171 words · 14 hyp34 ana11 exp

⚙️ Epigenetic Dysregulation Comparison -- AD/PD/ALS/FTD/HDKG

mechanism · 4,361 words · 54 hyp46 ana46 exp

⚙️ GBA1→GCase→Lysosome→PD Causal ChainKG

mechanism · 3,927 words · 14 hyp35 ana10 exp

⚙️ Lipid Metabolism Dysfunction Comparison — AD/PD/ALS/FTD/HDKG

mechanism · 3,831 words · 45 hyp41 ana46 exp

⚙️ Autophagy-Lysosomal Impairment Comparison — AD/PD/ALS/FTD/HDKG

mechanism · 3,688 words · 38 hyp37 ana45 exp

⚙️ Neuroinflammation Across AD, PD, ALS, FTD, and HDKG

mechanism · 3,668 words · 54 hyp54 ana47 exp

🏥 sporadic-familial-pd-comparisonKG

disease · 3,585 words · 24 hyp5 ana5 exp

🧪 Portable Driving Simulator for PD Assessment (NCT03969927)KG

clinical · 3,450 words · 2 hyp13 ana6 exp

⚙️ Autophagy Failure Comparison -- AD/PD/ALS/FTD/HDKG

mechanism · 3,424 words · 18 hyp39 ana37 exp

⚙️ Ion Channel Dysfunction in Parkinson's DiseaseKG

mechanism · 3,382 words · 18 hyp48 ana60 exp

⚙️ pink1-parkin-mitophagy-pd-causal-chainKG

mechanism · 3,341 words · 19 hyp36 ana18 exp

⚙️ Astrocyte Metabolic Enhancement Therapy for PDKG

mechanism · 3,337 words · 179 hyp67 ana21 exp

🧪 Vagal Nerve Stimulation for Parkinson's Disease (NCT07226284)KG

clinical · 3,330 words · 10 hyp15 ana59 exp

🧫 Experiment: Multi-Ethnic PD GWASKG

experiment · 3,302 words · 28 hyp29 ana7 exp

nct06365190-rtms-pdKG

clinical_trial · 3,270 words · 18 hyp3 ana16 exp

⚙️ VPS35 Retromer Dysfunction Parkinson's Disease Causal ChainKG

mechanism · 3,215 words · 6 hyp43 ana60 exp

⚙️ Shared Proteinostasis Failure in Alzheimer's and Parkinson's DiseaseKG

mechanism · 3,143 words · 30 hyp50 ana61 exp

🔧 Digital Therapeutics for Parkinson's DiseaseKG

technology · 3,124 words · 13 hyp18 ana71 exp

⚙️ PD-1/PD-L1 Immune Checkpoint Signaling in NeurodegenerationKG

mechanism · 3,120 words · 287 hyp56 ana54 exp

🧪 ND0612 Subcutaneous Levodopa Infusion PD Trial (NCT04006210)KG

clinical · 3,114 words · 12 hyp2 ana6 exp

📊 Alpha-Synuclein Seed Kinetic Staging in Parkinson's DiseaseKG

biomarker · 3,114 words · 13 hyp18 ana71 exp

ai-facial-speech-patterns-pd-nct07392411KG

clinical_trial · 3,086 words · 4 ana2 exp

🧬 ERP57 (PDIA3) — Protein Disulfide Isomerase Family A Member 3KG

gene · 3,072 words · 2 hyp5 ana13 exp

🧬 PDHX GeneKG

gene · 3,019 words · 11 hyp3 ana

🧬 pdp1KG

gene · 2,997 words · 2 hyp1 ana

🧬 PDCD10 Gene (Programmed Cell Death 10)KG

gene · 2,983 words · 10 hyp7 ana

ambroxol-aspro-pdKG

clinical_trial · 2,976 words · 6 hyp23 ana5 exp

⚙️ PD Failed Approaches AutopsyKG

mechanism · 2,975 words · 4 hyp43 ana4 exp

⚙️ Neuroinflammation in Alzheimer and Parkinson DiseaseKG

mechanism · 2,971 words · 46 hyp48 ana30 exp

🔬 Update TDP-43 protein page with comprehensive contentKG

protein · 2,951 words · 31 hyp25 ana3 exp

⚙️ Neuroinflammation in Parkinson's DiseaseKG

mechanism · 2,907 words · 20 hyp44 ana78 exp

⚙️ Neuroinflammation Comparison — AD/PD/ALS/FTD/HDKG

mechanism · 2,902 words · 36 hyp39 ana48 exp

⚙️ SAA and Imaging for Prodromal Parkinson's Disease Trial EnrichmentKG

mechanism · 2,893 words · 9 hyp43 ana67 exp

move-brain-pd-nct07299279KG

clinical_trial · 2,892 words · 17 hyp20 ana8 exp

📊 adpd-2026-seed-amplification-assaysKG

biomarker · 2,853 words · 16 hyp7 ana2 exp

adpd-2026-seed-amplification-assaysKG

general · 2,853 words · 5 hyp5 ana

🧪 NCT07172295: Low-Intensity Focused Ultrasound for PD TremorKG

clinical · 2,823 words · 1 hyp1 ana4 exp

⚙️ neuroinflammation-ad-pd-alsKG

mechanism · 2,818 words · 36 hyp56 ana41 exp

🧬 PDIA3 - Protein Disulfide Isomerase Family A Member 3KG

gene · 2,790 words · 5 hyp6 ana13 exp

⚙️ RAB39B Endosomal-Lysosomal Dysfunction PD Causal ChainKG

mechanism · 2,779 words · 18 hyp36 ana7 exp

💊 PD Drug Combination Therapy MatrixKG

therapeutic · 2,773 words · 29 hyp21 ana7 exp

🧬 PDPK1 GeneKG

gene · 2,764 words · 12 hyp3 ana

🧫 Alpha-Synuclein Spreading Mechanism — Prion-Like Propagation and NeurodegenerationKG

experiment · 2,761 words · 284 hyp52 ana68 exp

🏢 Taiwanese Biotechnology Companies in Parkinson's Disease

company · 2,756 words · 3 hyp14 ana59 exp

🧬 PDK4 (3-Phosphoinositide-Dependent Protein Kinase-4)KG

gene · 2,724 words · 24 hyp10 ana5 exp

⚙️ Neurovascular Coupling Disease Comparison — AD/PD/ALS/FTD/HDKG

mechanism · 2,700 words · 27 hyp46 ana31 exp

⚙️ PDLIM7 Epigenetic Activation in Parkinson's DiseaseKG

mechanism · 2,652 words · 40 hyp50 ana60 exp

accelerated-tms-apathy-pd-nct07399496KG

clinical_trial · 2,612 words · 1 hyp1 ana7 exp

📊 adpd-2026-precision-medicine-genetic-stratificationKG

biomarker · 2,612 words · 41 hyp11 ana14 exp

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