| Gene Symbol | PD |
| Reaction mixture | Contains recombinant alpha-synuclein monomer (substrate), Thioflavin T (fluorescent dye), and NaCl |
| Cycling conditions | Alternating periods of shaking (1 min) and rest (1 min) at 30°C for 30-100 hours |
| Detection | Thioflavin T fluorescence measured every 15-30 minutes |
| Positive response | Seed-induced aggregation causes increased fluorescence |
| Sensitivity | Can detect as few as 10-100 aggregated alpha-synuclein seeds[@okuzumi2023] |
| Associated Diseases | DEPRESSION, NEURODEGENERATION, T2DM |
| Known Drugs/Compounds | EPS |
| KG Connections | 59 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |