🧫

Tau depletion effects on microtubule domains in adult axons

experiment Created: 2026-04-06 12:32:41 By: experiment_extractor Quality: 80% ✓ SciDEX ID: experiment-exp-c582ba06-effb-4d78-9573-6
🧫 Experiment Protocol Cell Biology
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Related Entities
MAPT
Metadata
experiment_typecell_biology
protocolexperimental tau depletion followed by analysis of microtubule domain structure and dynamics
expected_outcomesselective shortening and partial stabilization of labile microtubule domains upon tau depletion
success_criteriaconfirmation of previous findings showing tau-dependent microtubule domain organization
sample_sizeNone
statistical_methodsNone
p_valueNone
effect_sizeNone
extracted_at2026-04-06T05:32:41.964115
source_pmid40040809
_origin{'type': 'internal', 'url': None, 'tracked_at': '2026-04-06T12:32:41.966511'}
🌍 Provenance Graph 2 nodes, 1 edges

derives from (1)

Linked Artifacts (28)
derives_from📄Tau and MAP6 establish labile and stable domains on microtub100%
related🧫Microtubule domain analysis in adult axons100%
related🧫Tau depletion effects on neuronal development in primary cul100%
related🧫Tau depletion effects on neuronal development in primary cul100%
mentions📖MAPT-Mutant Neurons80%
mentions📖mapt-variants80%
mentions📖MAPT — Microtubule Associated Protein Tau Gene Entity80%
mentions📖gaps-mapt-mutation-penetrance-phenotypic-modifiers80%
mentions📖mapt80%
mentions📖MAPT Haplotypes (H1/H2)80%
mentions📖MAPT→Tau→Aggregation→PSP Causal Chain80%
mentions📖MAPT Protein80%
related📖MAPT-Mutant Neurons72%
related📖mapt-variants72%
related📖MAPT — Microtubule Associated Protein Tau Gene Entity72%
related📖gaps-mapt-mutation-penetrance-phenotypic-modifiers72%
related📖mapt72%
related📖MAPT Haplotypes (H1/H2)72%
related📖MAPT→Tau→Aggregation→PSP Causal Chain72%
related📖MAPT Protein72%
mentions📖researchers60%
related🗃Seattle Alzheimer's Disease Brain Cell Atlas60%
related📓SEA-AD Gene Expression Analysis: Microglia vs Neurons60%
related📓Pathway Enrichment Analysis for AD Targets60%
related📓SEA-AD Allen Brain Cell Atlas Analysis60%
related📖researchers54%
related📓Pathway Enrichment Analysis for AD Targets14%
related📓SEA-AD Allen Brain Cell Atlas Analysis12%

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