🧫

Microtubule domain analysis in adult axons

experiment Created: 2026-04-06 12:32:06 By: experiment_extractor Quality: 80% ✓ SciDEX ID: experiment-exp-32576dcf-a6c7-4ff9-b7b8-3
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MAPT
Metadata
experiment_typecell_biology
protocolAnalysis of microtubule labile and stable domains in adult axons, tau depletion experiments
expected_outcomesConfirmation that adult axons show similar microtubule domain organization as juvenile neurons
success_criteriaDetection of distinct labile and stable domains on microtubules in adult axons
sample_sizeNone
statistical_methodsNone
p_valueNone
effect_sizeNone
extracted_at2026-04-06T05:32:06.632933
source_pmid40040809
_origin{'type': 'internal', 'url': None, 'tracked_at': '2026-04-06T12:32:06.635307'}
🌍 Provenance Graph 2 nodes, 1 edges

derives from (1)

Linked Artifacts (472)
derives_from📄Tau and MAP6 establish labile and stable domains on microtub100%
related🧫Tau depletion effects on neuronal development in primary cul100%
related🧫Tau depletion effects on neuronal development in primary cul100%
related🧫Tau depletion effects on microtubule domains in adult axons100%
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mentions📖4R Tauopathy Therapeutics — Investment Landscape Analysis44%
mentions📖ALS vs FTD: Comparative Investment Analysis44%
mentions📖Progressive Supranuclear Palsy (PSP) Investment Landscape44%
mentions📖Advanced Glycation End Products in 4R-Tauopathies - Cross-Di44%
mentions📖Apraxia in Corticobasal Syndrome44%
mentions📖Autophagy-Lysosomal Pathway Dysfunction in Corticobasal Synd44%
mentions📖Braak Staging and Tau Propagation Pathway44%
mentions📖Brainstem Circuit Vulnerability in PSP44%
mentions📖Mitochondrial Dysfunction in Corticobasal Degeneration44%
mentions📖CBS Tau Phosphorylation Pathways44%
mentions📖Chaperone-Mediated Proteostasis in 4R-Tauopathies44%
mentions📖Circular RNA Dysfunction in Neurodegeneration44%
mentions📖Complement and Coagulation Systems in 4R-Tauopathies44%
mentions📖Computational Models of Tau Propagation in Progressive Supra44%
mentions📖Contradiction Detection in Neurodegenerative Disease Researc44%
mentions📖Disease Progression Staging Synthesis44%
mentions📖Dystonia in Corticobasal Syndrome44%
mentions📖Environmental Toxins and Parkinson's Disease Risk44%
mentions📖Epigenetic Clocks in Brain Aging44%
mentions📖ER Stress and Unfolded Protein Response in 4R-Tauopathies44%
mentions📖evolutionary-scale-modeling-esm44%
mentions📖Exosome-Mediated Pathological Protein Propagation44%
mentions📖Extracellular Vesicles in Neurodegeneration44%
mentions📖Globular Glial Tauopathy (GGT) Neuropathology44%
mentions📖GRN Progranulin FTD Causal Chain44%
mentions📖GWAS Findings Hub: Alzheimer's and Parkinson's Dis44%
mentions📖Interoceptive Brain Dynamics in bvFTD44%
mentions📖Lipid Dysregulation in Neurodegeneration44%
mentions📖Lipid Metabolism Dysfunction Comparison — AD/PD/ALS/FTD/HD44%
mentions📖Microglial-Neuronal Interactions in Tauopathies44%
mentions📖mitochondrial-dysfunction-comparison44%
mentions📖mTOR Signaling Dysregulation in Progressive Supranuclear Pal44%
mentions📖Neuropeptide and GPCR Signaling in 4R-Tauopathies44%
mentions📖Neurotransmitter System Changes in 4R-Tauopathies: Cross-Dis44%
mentions📖Neurotransmitter System Dysfunction in 4R-Tauopathies44%
mentions📖Prion-Like Spread in Neurodegeneration44%
mentions📖Prognostic Biomarkers in Neurodegeneration44%
mentions📖Proteasome Dysfunction in Progressive Supranuclear Palsy44%
mentions📖Protein Aggregation Comparison in Neurodegeneration44%
mentions📖Protein Folding in Neurodegeneration44%
mentions📖psp-basal-ganglia-circuit-dysfunction44%
mentions📖Central Vestibular Pathway Vulnerability in Progressive Supr44%
mentions📖Mitochondrial Dysfunction in Progressive Supranuclear Palsy44%
mentions📖Olfactory Dysfunction in Progressive Supranuclear Palsy44%
mentions📖mechanisms-psp-prodromal-features44%
mentions📖Spatial Transcriptomics of Progressive Supranuclear Palsy44%
mentions📖RNA G-quadruplexes in Neurodegeneration44%
mentions📖RNA Metabolism in Alzheimer's Disease44%
mentions📖Selective Neuronal Vulnerability44%
mentions📖Selective Neuronal Vulnerability in Progressive Supranuclear44%
mentions📖Synaptic Plasticity Dysfunction in 4R-Tauopathies44%
mentions📖Synucleinopathy Mechanism44%
mentions📖Tau Aggregation Mechanisms in Progressive Supranuclear Palsy44%
mentions📖tau-hyperphosphorylation44%
mentions📖Tau Kinase Signaling Cascade in Alzheimer's Disease44%
mentions📖Tau Phosphorylation Pathway in Alzheimer's Disease44%
mentions📖Tau Post-Translational Modifications in 4R-Tauopathies44%
mentions📖TREM2 in FTD44%
mentions📖Ubiquitin-Proteasome System Dysfunction in 4R-Tauopathies44%
mentions📖PSP Japan — 日本PSP協会44%
mentions📖AlphaFold for Neurodegenerative Diseases44%
mentions📖Advanced Immunotherapy Platforms for Tau44%
mentions📖Anti-Tau Immunotherapy Programs44%
mentions📖Emerging Treatments for Corticobasal Syndrome44%
mentions📖CBS/PSP Clinical Trials Guide44%
mentions📖circRNA Dysfunction Restoration Therapy44%
mentions📖omega-3-fatty-acids-neurodegeneration44%
mentions📖Progressive Supranuclear Palsy (PSP) Treatment Guide44%
mentions📖Proteostasis Therapy CBS PSP44%
mentions📖RNA Targeting Therapy for Neurodegeneration44%
mentions📖Section 101: Microbiome-Gut-Brain Axis in CBS/PSP44%
mentions📖Section 102: Proteostasis Network Dysregulation in CBS/PSP44%
mentions📖section-197-advanced-clinical-trial-design-cbs-psp44%
mentions📖Computational Pharmacology and AI-Driven Drug Combination Op44%
mentions📖Section 217 Advanced Cell Therapy and Regenerative Medicine 44%
mentions📖Semorinemab (RG6100)44%
mentions📖Small Molecule Therapies in Neurodegenerative Diseases44%
mentions📖zagotenemab44%
related📓Pathway Enrichment Analysis for AD Targets14%
related📓SEA-AD Allen Brain Cell Atlas Analysis12%