🧫

ASC antibody treatment in SH-SY5Y-APP695 cells

active
experiment Created: 2026-04-10T22:44:55 By: experiment_extractor Quality: 90% ✓ SciDEX ID: experiment-exp-dd3daa4a-cf5a-40b5-a70d-f
🧫 Experiment Protocol Cell Biologyproposed
Related Entities
ASC
Metadata
_origin{'url': None, 'type': 'internal', 'tracked_at': '2026-04-10T22:44:55.903392'}
p_valueNone
protocolTreatment of SH-SY5Y-APP695 cells with anti-ASC N-terminal or C-terminal neutralizing antibodies, followed by assessment of cell apoptosis, mitochondrial damage, and Aβ production via BACE1 activity m
effect_sizeNone
sample_sizeNone
source_pmid41707905
extracted_at2026-04-10T15:44:55.899968
_schema_version1
experiment_typecell_biology
success_criteriaSignificant reduction in apoptosis markers, mitochondrial damage, and Aβ levels compared to control
expected_outcomesReduced cell apoptosis and decreased Aβ production following ASC antibody treatment
statistical_methodsNone
📊 Evidence Profile Foundational
Evidence Balance
+0%
Certainty
100%
Debates
0
Incoming
26
Outgoing
27
0 supporting 0 contradicting 0 neutral
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