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bace1

wiki page Created: 2026-04-02 13:40:08 By: crosslink-migration Quality: 50% ✓ SciDEX ID: wiki-genes-bace1
Related Entities
BACE1
Metadata
sluggenes-bace1
entity_typegene
kg_node_idBACE1
🌍 Provenance Graph 1 nodes, 0 edges

No provenance edges found

Linked Artifacts (139)
mentions🧪Palmitoylation-Targeted BACE1 Trafficking Disruptors90%
targets🧪Palmitoylation-Targeted BACE1 Trafficking Disruptors90%
analysis_target🔬Investigate how lipid raft composition (cholesterol metaboli80%
mentions🧪Palmitoylation-Targeted BACE1 Trafficking Disruptors80%
related🧪Palmitoylation-Targeted BACE1 Trafficking Disruptors80%
related🧪Palmitoylation-Targeted BACE1 Trafficking Disruptors80%
mentions🔬Investigate how lipid raft composition (cholesterol metaboli70%
mentions🧫ASC antibody treatment in SH-SY5Y-APP695 cells70%
mentions🧫Experimental: CAAR-T Cell Therapy for Autoantibody-Mediated 70%
mentions🧫ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De70%
mentions🧫Neural Stem Cell Therapy for Alzheimer's Disease70%
mentions🧫Experiment Validation: In vitro ThT Assay70%
related🔬Investigate how lipid raft composition (cholesterol metaboli70%
see_also🧪Palmitoylation-Targeted BACE1 Trafficking Disruptors70%
mentions🧪Multi-Modal Stress Response Harmonization65%
mentions🧪Dual-Domain Antibodies with Engineered Fc-FcRn Affinity Modu65%
mentions🧪CYP46A1 Overexpression Gene Therapy65%
mentions🧪APOE4 Allosteric Rescue via Small Molecule Chaperones65%
mentions🧪Membrane Cholesterol Gradient Modulators65%
mentions🧪Selective Acid Sphingomyelinase Modulation Therapy65%
mentions🧪Sphingomyelin Synthase Activators for Raft Remodeling65%
mentions🧪Excitatory Neuron Vulnerability via SLC17A7 Downregulation65%
mentions🔬Investigate how lipid raft composition (cholesterol metaboli63%
related🧫ASC antibody treatment in SH-SY5Y-APP695 cells63%
related🧫Experimental: CAAR-T Cell Therapy for Autoantibody-Mediated 63%
related🧫ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De63%
related🧫Neural Stem Cell Therapy for Alzheimer's Disease63%
related🧫Experiment Validation: In vitro ThT Assay63%
see_also📖ABCA7 (Redirect)60%
see_also📖ABCA1 - ATP-Binding Cassette Transporter A160%
see_also📖adam1060%
see_also📖ACE Gene60%
related🧪Multi-Modal Stress Response Harmonization58%
related🧪Dual-Domain Antibodies with Engineered Fc-FcRn Affinity Modu58%
related🧪CYP46A1 Overexpression Gene Therapy58%
related🧪APOE4 Allosteric Rescue via Small Molecule Chaperones58%
related🧪Membrane Cholesterol Gradient Modulators58%
related🧪Selective Acid Sphingomyelinase Modulation Therapy58%
related🧪Sphingomyelin Synthase Activators for Raft Remodeling58%
related🧪Excitatory Neuron Vulnerability via SLC17A7 Downregulation58%
mentions🧪SASP-Mediated Cholinergic Synapse Disruption50%
mentions🧪Biorhythmic Interference via Controlled Sleep Oscillations50%
mentions🧪LRP1-Dependent Tau Uptake Disruption50%
mentions🧪APOE-Mediated Synaptic Lipid Raft Stabilization50%
mentions🧪Circadian-Synchronized LRP1 Pathway Activation50%
mentions🧪Blood-Brain Barrier SPM Shuttle System50%
mentions🧫Experimental: CAAR-T Cell Therapy for Autoantibody-Mediated 50%
mentions🧫ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De50%
mentions🧫Neural Stem Cell Therapy for Alzheimer's Disease50%
mentions🧫Experiment Validation: In vitro ThT Assay50%
mentions🧪Multi-Modal Stress Response Harmonization50%
mentions🧪Dual-Domain Antibodies with Engineered Fc-FcRn Affinity Modu50%
mentions🧪CYP46A1 Overexpression Gene Therapy50%
mentions🧪Epigenetic Memory Reprogramming for Alzheimer's Disease50%
mentions🧪APOE4 Allosteric Rescue via Small Molecule Chaperones50%
mentions🧪Membrane Cholesterol Gradient Modulators50%
mentions🧪Selective Acid Sphingomyelinase Modulation Therapy50%
mentions🧪Sphingomyelin Synthase Activators for Raft Remodeling50%
mentions🧪APOE Isoform Expression Across Glial Subtypes50%
mentions🧪Osmotic Gradient Restoration via Selective AQP1 Enhancement 50%
mentions🧪Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna50%
mentions🧪Circadian Rhythm Entrainment of Reactive Astrocytes50%
mentions🧪Temporal Decoupling via Circadian Clock Reset50%
mentions🧪Circadian Clock-Autophagy Synchronization50%
mentions🧪GFAP-Positive Reactive Astrocyte Subtype Delineation50%
mentions🧪Perforant Path Presynaptic Terminal Protection Strategy50%
mentions🧪Nutrient-Sensing Epigenetic Circuit Reactivation50%
mentions🧪Mitochondrial-Nuclear Epigenetic Cross-Talk Restoration50%
mentions🧪SIRT3-Mediated Mitochondrial Deacetylation Failure with PINK50%
mentions🧪TREM2 Conformational Stabilizers for Synaptic Discrimination50%
mentions🧪TREM2-mediated microglial tau clearance enhancement50%
mentions🧪Cell-Type Specific TREM2 Upregulation in DAM Microglia50%
mentions🧪APOE Isoform Conversion Therapy50%
mentions🧪APOE4-Selective Lipid Nanoemulsion Therapy50%
mentions🧪APOE-TREM2 Interaction Modulation50%
mentions🧪TREM2-Mediated Selective Aggregate Clearance Pathway50%
mentions🧪TREM2-Dependent Microglial Senescence Transition50%
mentions🧪Epigenetic Memory Reprogramming for Alzheimer's Disease50%
related🔬What are the mechanisms underlying blood-brain barrier trans50%
related🔬What are the mechanisms underlying microglia-astrocyte cross50%
related🔬What are the mechanisms underlying senolytic therapy for age50%
related🔬What are the mechanisms underlying neuroinflammation resolut50%
related🔬Investigate prion-like spreading of tau pathology through co50%
related🔬What are the mechanisms underlying blood-brain barrier trans50%
related🔬What are the mechanisms underlying microglia-astrocyte cross50%
related🔬What are the mechanisms underlying apoe4 structural biology 50%
related🔬What are the mechanisms underlying digital biomarkers and ai50%
related🔬What are the mechanisms underlying senolytic therapy for age50%
related🔬What are the mechanisms underlying neuroinflammation resolut50%
related🔬What are the mechanisms underlying mechanistic role of apoe 50%
related🔬Analyze circuit-level changes in neurodegeneration using All50%
related🔬CRISPR-based therapeutic approaches for neurodegenerative di50%
related🔬Investigate prion-like spreading of tau pathology through co50%
related🔬What are the mechanisms underlying perivascular spaces and g50%
related🔬Cell type vulnerability in Alzheimers Disease (SEA-AD transc50%
related🔬Investigate how lipid raft composition (cholesterol metaboli48%
mentions📖Actinogen Medical40%
mentions📖Daewoong Pharmaceutical40%
mentions📖Eisai Co., Ltd.40%
mentions📖Hanmi Pharmaceutical40%
mentions📖Innovent Biologics40%
mentions📖JW Pharmaceutical40%
mentions📖Nippon Shinyaku Co., Ltd.40%
mentions📖Ono Pharmaceutical40%
mentions📖RNP Inc.40%
mentions📖University of Strasbourg40%
mentions🔬Analyze circuit-level changes in neurodegeneration using All40%
related🧪Smartphone-Detected Motor Variability Correction40%
related🧪Circadian-Synchronized Proteostasis Enhancement40%
related🧪Selective APOE4 Degradation via Proteolysis Targeting Chimer40%
related🧪Ganglioside Rebalancing Therapy40%
related🧪Retinal Vascular Microcirculation Rescue40%
related🧪Chaperone-Mediated APOE4 Refolding Enhancement40%
related🧪Ocular Immune Privilege Extension40%
related🧪Interfacial Lipid Mimetics to Disrupt Domain Interaction40%
related🧪Pharmacological Enhancement of APOE4 Glycosylation40%
related🧪Flotillin-1 Stabilization Compounds40%
related🧪Targeted APOE4-to-APOE3 Base Editing Therapy40%
related🧪Digital Twin-Guided Metabolic Reprogramming40%
related🧪Competitive APOE4 Domain Stabilization Peptides40%
related🧪Vocal Cord Neuroplasticity Stimulation40%
related🧪SASP-Mediated Cholinergic Synapse Disruption40%
related🧪Biorhythmic Interference via Controlled Sleep Oscillations40%
related🧪LRP1-Dependent Tau Uptake Disruption40%
related🧪Circadian-Synchronized LRP1 Pathway Activation40%
related🧪Blood-Brain Barrier SPM Shuttle System40%
related🔬What are the mechanisms underlying apoe4 structural biology 40%
related🔬APOE4 differs from APOE3 by C112R causing domain interaction40%
related🔬What are the mechanisms underlying digital biomarkers and ai40%
related🔬Can speech, gait, retinal imaging, sleep, and smartphone dat40%
mentions🔬What are the mechanisms underlying blood-brain barrier trans35%
mentions🔬What are the mechanisms underlying microglia-astrocyte cross35%
mentions🔬What are the mechanisms underlying apoe4 structural biology 35%
mentions🔬What are the mechanisms underlying digital biomarkers and ai35%
mentions🔬What are the mechanisms underlying senolytic therapy for age35%
mentions🔬What are the mechanisms underlying neuroinflammation resolut35%
mentions🔬What are the mechanisms underlying mechanistic role of apoe 35%
mentions🔬CRISPR-based therapeutic approaches for neurodegenerative di35%
mentions🔬Investigate prion-like spreading of tau pathology through co35%
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