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Prolonged anesthesia induces neuroinflammation and complement-mediated microglial synaptic elimination involved in neurocognitive dysfunction and anxiety-like behaviors.

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paper Created: 2026-04-03T07:10:32 By: crosslink_script Quality: 90% 🔗 External ID: paper-36600274
📄 Paper Details
Prolonged anesthesia induces neuroinflammation and complement-mediated microglial synaptic elimination involved in neurocognitive dysfunction and anxiety-like behaviors.
Xu F, Han L, Wang Y, Deng D, Ding Y, Zhao S, Zhang Q, Ma L, Chen X
BMC Med PubMed DOI
Abstract

1. BMC Med. 2023 Jan 5;21(1):7. doi: 10.1186/s12916-022-02705-6. Prolonged anesthesia induces neuroinflammation and complement-mediated microglial synaptic elimination involved in neurocognitive dysfunction and anxiety-like behaviors. Xu F(#)(1), Han L(#)(1), Wang Y(1), Deng D(1), Ding Y(1), Zhao S(1), Zhang Q(2), Ma L(1), Chen X(3). Author information: (1)Department of Anesthesiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, Hu...

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📊 Evidence Profile
Evidence Balance
+0%
Certainty
30%
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Outgoing
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