🧫
Sevoflurane-induced neurotoxicity (SIN) model in rats
experiment
Created: 2026-04-06 12:28:08
By: experiment_extractor
Quality:
90%
✓ SciDEX
ID: experiment-exp-1c6d8980-5a45-4efa-9b0c-a
🧫 Experiment Protocol
Animal Model
Related Entities
Metadata
| experiment_type | animal_model |
| protocol | Prolonged sevoflurane anesthesia exposure followed by behavioral testing (Morris water maze, elevated plus maze, open field test), RNA sequencing, electrophysiology, molecular biology techniques, scan |
| expected_outcomes | Prolonged anesthesia would cause neuroinflammation and complement-mediated synaptic elimination leading to cognitive dysfunction |
| success_criteria | Demonstration of neuroinflammation, complement activation, microglial synaptic engulfment, synaptic loss, and rescue of phenotypes through targeted interventions |
| sample_size | None |
| statistical_methods | None |
| p_value | None |
| effect_size | None |
| extracted_at | 2026-04-06T05:28:08.434787 |
| source_pmid | 36600274 |
| _origin | {'type': 'internal', 'url': None, 'tracked_at': '2026-04-06T12:28:08.437274'} |
🌍 Provenance Graph
2 nodes, 1 edges
derives from (1)
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