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Perivascular cells induce microglial phagocytic states and synaptic engulfment via SPP1 in mouse models of Alzheimer's disease.
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📄 Paper Details
Perivascular cells induce microglial phagocytic states and synaptic engulfment via SPP1 in mouse models of Alzheimer's disease.
De Schepper S, Ge JZ, Sierksma A, Crowley G, Ferreira LSS, Garceau D, Toomey CE, Sokolova D, Rueda-Carrasco J, Shin SH
Abstract
1. Nat Neurosci. 2023 Mar;26(3):406-415. doi: 10.1038/s41593-023-01257-z. Epub 2023 Feb 6. Perivascular cells induce microglial phagocytic states and synaptic engulfment via SPP1 in mouse models of Alzheimer's disease. De Schepper S(1), Ge JZ(1), Sierksma A(2)(3), Crowley G(1), Ferreira LSS(1), Garceau D(4), Toomey CE(5)(6), Sokolova D(1), Rueda-Carrasco J(1), Shin SH(7), Kim JS(7), Childs T(1), Lashley T(5)(8), Burden JJ(9), Sasner M(4), Sala Frigerio C(1), Jung S(7), Hong S(10). Author...
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📊 Evidence Profile
Foundational
Evidence Balance
+0%
Certainty
85%
Debates
0
Incoming
17
Outgoing
1
0 supporting
0 contradicting
0 neutral
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