🧫
Sevoflurane-induced neurotoxicity (SIN) rat model
active
experiment
Created: 2026-04-06T12:28:17
By: experiment_extractor
Quality:
95%
✓ SciDEX
ID: experiment-exp-aff90cc4-5f5c-48ea-a980-c
🧫 Experiment Protocol
Animal Modelproposed
Related Entities
▸Metadata
| _origin | {'url': None, 'type': 'internal', 'tracked_at': '2026-04-06T12:28:17.571571'} |
| p_value | None |
| protocol | Prolonged sevoflurane anesthesia followed by behavioral testing (Morris water maze, elevated plus maze, open field test), transcriptomic analysis, electrophysiology, molecular biology assays, scanning |
| effect_size | None |
| sample_size | None |
| source_pmid | 36600274 |
| extracted_at | 2026-04-06T05:28:17.569122 |
| _schema_version | 1 |
| experiment_type | animal_model |
| success_criteria | Demonstration of behavioral deficits, neuroinflammation markers, complement activation, and synaptic elimination |
| expected_outcomes | Neuroinflammation, microglial activation, complement activation, synaptic loss, cognitive impairment, and anxiety-like behaviors |
| statistical_methods | None |
📊 Evidence Profile
Foundational
Evidence Balance
+0%
Certainty
100%
Debates
0
Incoming
39
Outgoing
41
0 supporting
0 contradicting
0 neutral
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