📄
Genome-wide association meta-analysis identifies 17 loci associated with nonalcoholic fatty liver disease.
active
paper
Created:
By: unknown
Quality:
50%
✓ SciDEX
ID: paper-37709864
📄 Paper Details
Genome-wide association meta-analysis identifies 17 loci associated with nonalcoholic fatty liver disease.
["Chen Y", "Du X", "Kuppa A", "Feitosa M", "Bielak L", "O'Connell J", "Musani S", "Guo X", "Kahali B", "Chen V"]
Abstract
Nonalcoholic fatty liver disease (NAFLD) is common and partially heritable and has no effective treatments. We carried out a genome-wide association study (GWAS) meta-analysis of imaging (n = 66,814) and diagnostic code (3,584 cases versus 621,081 controls) measured NAFLD across diverse ancestries. We identified NAFLD-associated variants at torsin family 1 member B (TOR1B), fat mass and obesity associated (FTO), cordon-bleu WH2 repeat protein like 1 (COBLL1)/growth factor receptor-bound protein ...
▸Metadata
| _schema_version | 1 |
📊 Evidence Profile
Evidence Balance
+0%
Certainty
5%
Debates
0
Incoming
1
Outgoing
1
0 supporting
0 contradicting
0 neutral
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.