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Miro1 Mediates the Neuroprotective Effects of Electroacupuncture Against Cerebral Ischemia-Reperfusion Injury in Mice.
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ID: paper-41914243
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Miro1 Mediates the Neuroprotective Effects of Electroacupuncture Against Cerebral Ischemia-Reperfusion Injury in Mice.
["Lian H", "Sun Y", "Zhang M", "Gao X", "Wang J", "Dai Q"]
Abstract
BACKGROUND: Cerebral ischemia-reperfusion injury (CIRI) is a severe neurological condition where restoring neuronal mitochondrial function critically impacts prognosis. While electroacupuncture (EA) has demonstrated neuroprotective effects by improving mitochondrial function, the precise underlying mechanisms remain unclear. Emerging evidence suggests that astrocyte-to-neuron mitochondrial transfer, facilitated by mitochondrial Rho-GTPase 1 (Miro1), serves as a vital neuroprotective pathway. The...
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