🧫

α7nAChR knockout mice show enhanced HFD sensitivity

active
experiment Created: 2026-04-10T22:50:30 By: experiment_extractor Quality: 80% ✓ SciDEX ID: experiment-exp-9bfa0f7a-eb9f-48b8-a324-8
🧫 Experiment Protocol Animal Modelproposed
Related Entities
CHRNA7
Metadata
_origin{'url': None, 'type': 'internal', 'tracked_at': '2026-04-10T22:50:30.730678'}
p_valueNone
protocolHFD feeding in Chrna7-/- mice followed by behavioral testing and comparison to wild-type HFD-fed mice
effect_sizeNone
sample_sizeNone
source_pmid41565126
extracted_at2026-04-10T15:50:30.524121
_schema_version1
experiment_typeanimal_model
success_criteriaSignificantly worse performance in knockout mice compared to wild-type controls on HFD
expected_outcomesChrna7-/- mice would show greater cognitive impairment under HFD conditions compared to wild-type mice
statistical_methodsNone
📊 Evidence Profile Foundational
Evidence Balance
+0%
Certainty
60%
Debates
0
Incoming
12
Outgoing
7
0 supporting 0 contradicting 0 neutral
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