gene

AHI1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about AHI1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

7Connections

0Hypotheses

0Analyses

5Outgoing

2Incoming

0Experiments

0Debates

Summary

Abelson Helper Integration Site 1

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🧬 Gene Info

Gene Symbol	AHI1
Full Name	Abelson Helper Integration Site 1
Chromosome	6q24.3
Protein Type	Receptor
Function	It plays critical roles in ciliary signaling, neuronal migration, and synaptic function.
Primary Expression	regions affected in Parkinson disease
UniProt ID	Q8N398
NCBI Gene ID	55306
Ensembl ID	ENSG00000135541
OMIM	608429
GeneCards	AHI1
Human Protein Atlas	AHI1
Associated Diseases	neurodegeneration
Interactions	ASTROCYTES, BCL2, GENES, MICROGLIA
KG Connections	7 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: AHI1 — AlphaFold Q8N398 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

Abelson Helper Integration Site 1

gene · 921 words

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Pathway Diagram

graph TD
    AHI1["AHI1"]
    Multiple_Sclerosis{"Multiple Sclerosis"}
    AHI1 -->|"interacts with"| Multiple_Sclerosis
    Ms{"Ms"}
    AHI1 -->|"activates"| Ms
    BCL2["BCL2"]
    AHI1 -->|"activates"| BCL2
    GENES["GENES"]
    AHI1 -->|"interacts with"| GENES
    MICROGLIA["MICROGLIA"]
    AHI1 -->|"activates"| MICROGLIA
    AND["AND"]
    AHI1 -->|"interacts with"| AND
    neurodegeneration["neurodegeneration"]
    AHI1 -->|"implicated in"| neurodegeneration
    GENES -->|"interacts with"| AHI1
    ASTROCYTES["ASTROCYTES"]
    ASTROCYTES -->|"activates"| AHI1
    style AHI1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (5)

Target	Relation	Type	Str
Multiple Sclerosis	interacts_with	disease	0.65
Ms	activates	disease	0.65
BCL2	activates	gene	0.60
GENES	interacts_with	gene	0.60
MICROGLIA	activates	gene	0.60

Incoming (2)

Source	Relation	Type	Str
ASTROCYTES	activates	gene	0.60
GENES	interacts_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning AHI1 in their description or question text

No additional research found