Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about ap2m1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | AP2M1 |
| Full Name | Adaptor Related Protein Complex 2 Subunit Mu 1 |
| Chromosome | 3p24.3 |
| Function | is a hydrophobic residue). |
| Molecular Weight | 50 kDa |
| Amino Acids | 435 aa |
| Exons | 16 |
| UniProt ID | Q96CW1 |
| NCBI Gene ID | 1173 |
| Ensembl ID | ENSG00000161298 |
| OMIM | 601024 |
| GeneCards | AP2M1 |
| Human Protein Atlas | AP2M1 |
| Associated Diseases | Alzheimer's Disease |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
flowchart TD
N0["AP2M1"]
N1["AUTOPHAGY"]
N0 -->|"activates"| N1
N2["LC3"]
N0 -->|"activates"| N2
N3["Autophagy"]
N0 -->|"activates"| N3
N4["Endocytosis"]
N0 -->|"activates"| N4
N5["AP2A1"]
N5 -->|"activates"| N0
N6["AND"]
N6 -->|"activates"| N0
N2 -->|"activates"| N0
N7["neurodegeneration"]
N0 -->|"implicated in"| N7
classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
classDef therapeutic fill:#1a2a2a,stroke:#26a69a,color:#e0e0e0
class N1 gene
class N2 gene
class N3 pathway
class N4 pathway
class N5 gene
class N6 gene| Target | Relation | Type | Str |
|---|---|---|---|
| ds-83b31ef18d49 | provides_data_for | dataset | 1.00 |
| LC3 | activates | gene | 0.60 |
| AUTOPHAGY | activates | gene | 0.60 |
| Autophagy | activates | pathway | 0.60 |
| Endocytosis | activates | pathway | 0.60 |
| benchmark_ot_ad_answer_key:AP2M1 | data_in | dataset_row | 0.00 |
| Source | Relation | Type | Str |
|---|---|---|---|
| ds-83b31ef18d49 | data_in | dataset | 1.00 |
| AP2A1 | activates | gene | 0.60 |
| LC3 | activates | gene | 0.60 |
| AND | activates | gene | 0.60 |
| benchmark_ot_ad_answer_key:AP2M1 | data_in | dataset_row | 0.00 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||