gene

ap2m1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about ap2m1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

11Connections
0Hypotheses
0Analyses
6Outgoing
5Incoming

No summary available yet. View on Wiki →

🧬 Gene Info
Gene SymbolAP2M1
Full NameAdaptor Related Protein Complex 2 Subunit Mu 1
Chromosome3p24.3
Functionis a hydrophobic residue).
Molecular Weight50 kDa
Amino Acids435 aa
Exons16
UniProt IDQ96CW1
NCBI Gene ID1173
Ensembl IDENSG00000161298
OMIM601024
GeneCardsAP2M1
Human Protein AtlasAP2M1
Associated DiseasesAlzheimer's Disease
DatabasesGeneCardsHPASTRING
🔮 Predicted Structure: ap2m1 — AlphaFold Q96CW1 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (8)

Knowledge base pages for this entity

AP2M1 Gene

gene · 3193 words

ARRB2 — Arrestin Beta 2

gene · 2401 words

SND1 — Stonin 1

gene · 2073 words

AP2B1 — Adaptor Related Protein Complex 2 Subunit Beta 1

gene · 1174 words

ap2a1

gene · 1154 words

Pathway Diagram

flowchart TD
    N0["AP2M1"]
    N1["AUTOPHAGY"]
    N0 -->|"activates"| N1
    N2["LC3"]
    N0 -->|"activates"| N2
    N3["Autophagy"]
    N0 -->|"activates"| N3
    N4["Endocytosis"]
    N0 -->|"activates"| N4
    N5["AP2A1"]
    N5 -->|"activates"| N0
    N6["AND"]
    N6 -->|"activates"| N0
    N2 -->|"activates"| N0
    N7["neurodegeneration"]
    N0 -->|"implicated in"| N7

    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    classDef therapeutic fill:#1a2a2a,stroke:#26a69a,color:#e0e0e0
    class N1 gene
    class N2 gene
    class N3 pathway
    class N4 pathway
    class N5 gene
    class N6 gene

Outgoing (6)

TargetRelationTypeStr
ds-83b31ef18d49provides_data_fordataset1.00
LC3activatesgene0.60
AUTOPHAGYactivatesgene0.60
Autophagyactivatespathway0.60
Endocytosisactivatespathway0.60

Incoming (5)

SourceRelationTypeStr
ds-83b31ef18d49data_indataset1.00
AP2A1activatesgene0.60
LC3activatesgene0.60
ANDactivatesgene0.60
benchmark_ot_ad_answer_key:AP2M1data_indataset_row0.00

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found