concept

CD8+ T CELLS

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CD8+ T CELLS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

20Connections

0Hypotheses

3Analyses

7Outgoing

13Incoming

0Experiments

3Debates

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💡 Concept Info

Name	CD8+ T CELLS
Related Pathways	CGAS-STING PATHWAY, STING PATHWAY

Pathway Diagram

graph TD
    CD8__T_CELLS[CD8+ T CELLS]
    CD8__T_CELLS -->|involved_in| Immune_Effector_Processes[Immune Effector Processes]
    CD8__T_CELLS -->|activates| ferroptosis[ferroptosis]
    C1q__tumor_associated_macropha[C1q+ tumor-associated macrophages] -->|inhibits| CD8__T_CELLS
    TIMP1[TIMP1] -->|mediates| CD8__T_CELLS
    CD161[CD161] -->|expressed in| CD8__T_CELLS
    STING[STING] -->|promotes| CD8__T_CELLS
    Immunosuppression[Immunosuppression] -->|downregulates| CD8__T_CELLS
    GAPDH[GAPDH] -->|expresses| CD8__T_CELLS
    salidroside[salidroside] -->|regulates| CD8__T_CELLS
    STING_PATHWAY[STING PATHWAY] -->|interacts| CD8__T_CELLS

Outgoing (7)

Target	Relation	Type	Str
neurodegeneration	modulates	disease	0.90
Immune Effector Processes	involved_in	process	0.88
PARKINSON'S DISEASE	associated_with	disease	0.80
Parkinson's Disease	associated_with	disease	0.80
myelinated axon degeneration	causes	phenotype	0.70
ferroptosis	activates	phenotype	0.70
oligodendrocyte damage	causes	cell_type	0.70

Incoming (13)

Source	Relation	Type	Str
C1q+ tumor-associated macrophages	inhibits	cell_type	0.90
TIMP1	mediates	gene	0.90
31915375	patrol	paper	0.90
CD161	expressed_in	protein	0.90
STING	promotes	protein	0.85
Immunosuppression	downregulates	process	0.82
CXCL10	associated_with	entity	0.80
STING	activates	protein	0.80
GAPDH	expresses	gene	0.80
salidroside	regulates	drug	0.70
STING PATHWAY	interacts_with	pathway	0.65
STING PATHWAY	associated_with	pathway	0.50
CGAS-STING PATHWAY	associated_with	pathway	0.50