protein

CDC37PROTEIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CDC37PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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0Hypotheses

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No summary available yet. View on Wiki →

🔬 Protein Info

Gene Symbol	CDC37
Full Name	Cell Division Cycle 37
Chromosome	19p13.3
Protein Type	Chaperone
Function	CDC37 (Cell Division Cycle 37) is an Hsp90 co-chaperone that specifically facilitates the folding and maturation of protein kinases.
Primary Expression	many cancers
Pathways	Chaperone
UniProt ID	P16234
NCBI Gene ID	2881
Ensembl ID	ENSG00000105401
OMIM	164860
GeneCards	CDC37
Human Protein Atlas	CDC37
Modification	Effect
Phosphorylation (Ser/Thr)	Modulates Hsp90 interaction, client release
Associated Diseases	Als, Cancer, Tumor
Interactions	PINK1, HSP90
KG Connections	15 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: CDC37PROTEIN — AlphaFold P16234 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

CDC37 (Cell Division Cycle 37) Protein

protein · 1392 words

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Pathway Diagram

graph TD
    CDC37PROTEIN["CDC37PROTEIN"]
    neurodegeneration["neurodegeneration"]
    CDC37PROTEIN -->|"implicated_in"| neurodegeneration
    style CDC37PROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
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Incoming (0)

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No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity