HSP90

Understanding Entity Pages

This page aggregates everything SciDEX knows about HSP90: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

HSP90 is a protein involved in neurodegeneration research. Key relationships include: co discussed, protects against, activates. Associated with ALS, Inflammation, Neuroinflammation. Connected to 21 entities in the SciDEX knowledge graph.

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graph TD
    HSP90["<b>HSP90</b>"]
    Neuroinflammation{"Neuroinflammation"}
    HSP90 -->|"protects against"| Neuroinflammation
    ALS{"ALS"}
    HSP90 -->|"activates"| ALS
    Inflammation{"Inflammation"}
    HSP90 -->|"protects against"| Inflammation
    SFRP1["SFRP1"]
    HSP90 -->|"interacts with"| SFRP1
    INFLAMMATION["INFLAMMATION"]
    HSP90 -->|"protects against"| INFLAMMATION
    AXON["AXON"]
    HSP90 -->|"activates"| AXON
    NEUROINFLAMMATION["NEUROINFLAMMATION"]
    HSP90 -->|"protects against"| NEUROINFLAMMATION
    Schwann_Cell["Schwann Cell"]
    HSP90 -->|"expressed in"| Schwann_Cell
    Macrophage["Macrophage"]
    HSP90 -->|"expressed in"| Macrophage
    MACROPHAGE["MACROPHAGE"]
    HSP90 -->|"co discussed"| MACROPHAGE
    MACROPHAGES["MACROPHAGES"]
    HSP90 -->|"co discussed"| MACROPHAGES
    HSP90 -->|"co discussed"| NEUROINFLAMMATION
    AND["AND"]
    AND -->|"regulates"| HSP90
    AXON -->|"activates"| HSP90
    INFLAMMATION -->|"protects against"| HSP90
    style HSP90 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0