protein

CLCN7PROTEIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CLCN7PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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0Hypotheses

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Summary

Clc 7 Chloride Channel is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.

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🔬 Protein Info

Gene Symbol	CLCN7PROTEIN
Full Name	ClC-7 Chloride Channel
Chromosome	3p21.31.
Protein Family	CLC chloride channel family
Protein Type	Channel
Function	is an important component in the neurobiology of neurodegenerative diseases.
Primary Expression	Ubiquitous (brain, bone, kidney, liver)
Subcellular Localization	in late endosomes and lysosomes Citation needed
Molecular Weight	~89 kDa
UniProt ID	P51798
GeneCards	CLCN7PROTEIN
Human Protein Atlas	CLCN7PROTEIN
Brain	High expression in neurons, especially in hippocampus and cortex
Bone	Osteoclasts highly express ClC-7 for bone resorption
Kidney	Proximal tubule cells
Associated Diseases	neurodegeneration
Interactions	AMPD2, GNAI3, GNPTG, WDR81
KG Connections	23 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: CLCN7PROTEIN — AlphaFold P51798 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

ClC-7 Chloride Channel

protein · 898 words

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Pathway Diagram

graph TD
    CLCN7PROTEIN["CLCN7PROTEIN"]
    neurodegeneration["neurodegeneration"]
    CLCN7PROTEIN -->|"implicated_in"| neurodegeneration
    style CLCN7PROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning CLCN7PROTEIN in their description or question text

No additional research found