Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about CNS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| MFSD2A-Targeted Lysophosphatidylcholine-SPM Conjugates as CN | 0.552 | neuropharmacology | What determines blood-brain barrier pene |
| Pharmacogenomic CNS Drug Optimization Platform | 0.534 | neurodegeneration | How do neurodegeneration gene expression |
Scientific analyses that reference this entity
drug delivery | 2026-04-15 | 0 hypotheses
neuropharmacology | 2026-04-13 | 2 hypotheses Top: 0.552
neurodegeneration | 2026-04-07 | 0 hypotheses
neurodegeneration | 2026-04-04 | 0 hypotheses
neurodegeneration | 2026-04-04 | 0 hypotheses
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| Geniposidic Acid Targeting FXR "S332 and H447" Mediated Conformational Change to [PMID:39998442] | Fan M, Xu Y, Wu B, Long J, Liu C et al. | Adv Sci (Weinh) | 2025 | 0 |
| Pharmacogenomics of Alzheimer's Disease: Novel Strategies for Drug Utilization a [PMID:36068470] | Cacabelos R, Naidoo V, Martínez-Iglesias | Methods Mol Biol | 2022 | 0 |
| Cannabis sativa: Much more beyond Δ(9)-tetrahydrocannabinol. [PMID:32335286] | Alves P, Amaral C, Teixeira N, Correia-d | Pharmacol Res | 2020 | 0 |
| The pharmacogenomics of valproic acid. [PMID:28878340] | Zhu MM, Li HL, Shi LH, Chen XP, Luo J et | J Hum Genet | 2017 | 0 |
| Ocular pharmacology. [PMID:26360129] | Novack GD, Robin AL | J Clin Pharmacol | 2016 | 0 |
| 1,4-Dihydropyridine scaffold in medicinal chemistry, the story so far and perspe [PMID:22709009] | Carosati E, Ioan P, Micucci M, Broccatel | Curr Med Chem | 2012 | 0 |
| ABC transporters and cytochromes P450 in the human central nervous system: influ [PMID:20843279] | Dutheil F, Jacob A, Dauchy S, Beaune P, | Expert Opin Drug Metab Toxicol | 2010 | 0 |