cell 1,109 words KG: oligodendrocytes 2026-03-22
kind:cell-typesection:cell-typesstate:published
Contents

Oligodendrocytes in CNS Myelination

🧫 Cell Type Info
Cell Typeoligodendrocytes
Definition<table class="infobox infobox-cell">
Key MarkersTAU, myelin, HSPA1A, SMS2, GPR37, PIEZO1, GBA1, Prosaposin
Key PathwaysDna Damage Response, sphingolipid metabolism, complement cascade, pyroptosis, unfolded protein response
Associated DiseasesAlzheimer's Disease, Parkinson's Disease, aging, Alzheimer's disease, Alzheimer'S Disease, Vascular Dementia
Linked Hypotheses114 hypotheses

Knowledge Graph

Related Hypotheses (30)

Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.68
CYP46A1 Overexpression Gene Therapy
Score: 0.63
Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.59
SASP-Driven Aquaporin-4 Dysregulation
Score: 0.59
Prefrontal sensory gating circuit restoration via PV interne
Score: 0.59

Related Analyses (21)

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neurodegeneration · archived
Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
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Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archived

See Also (4)

Aging vs Neurodegeneration: Mechanistic Comparison Matr
mechanism · KG edge: activates
Packard Center for ALS Research
institution · KG edge: associated_with
Alzheimer Indonesia
institution · KG edge: associated_with
ABCA1 - ATP-Binding Cassette Transporter A1
gene · KG edge: expressed_in

Knowledge Graph (12 edges)

oligodendrocytes activates neuroinflammation
oligodendrocytes activates neurodegeneration
oligodendrocytes produces myelin
oligodendrocytes involved_in myelin dysfunction
oligodendrocytes activates multiple sclerosis
oligodendrocytes interacts_with multiple sclerosis
oligodendrocytes causes Parkinson's disease
oligodendrocytes causes neurodegeneration
oligodendrocytes causes neuroinflammation
oligodendrocytes activates Parkinson's disease