Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about CANCER DEVELOPMENT: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | CANCER DEVELOPMENT |
Knowledge base pages for this entity
graph TD
CANCER_DEVELOPMENT["CANCER DEVELOPMENT"]
Autophagy["Autophagy"] -->|"modulates"| CANCER_DEVELOPMENT
circFRMD4A["circFRMD4A"] -->|"inhibits"| CANCER_DEVELOPMENT
LncRNA["LncRNA"] -->|"involved_in"| CANCER_DEVELOPMENT
MYC["MYC"] -->|"risk_factor_for"| CANCER_DEVELOPMENT
Circadian_Rhythm_Disruption["Circadian Rhythm Disruption"] -->|"contributes to"| CANCER_DEVELOPMENT
PI3K_AKT_mTOR_Pathway_Alterati["PI3K/AKT/mTOR Pathway Alterations"] -->|"contributes to"| CANCER_DEVELOPMENT
Cgas_Sting_Signaling["Cgas/Sting Signaling"] -->|"involved_in"| CANCER_DEVELOPMENT
AIMP2_DX2["AIMP2-DX2"] -->|"causes"| CANCER_DEVELOPMENT| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| Autophagy | associated_with | process | 0.95 |
| Autophagy | modulates | process | 0.95 |
| circFRMD4A | inhibits | compound | 0.92 |
| PRMT1 | associated_with | gene | 0.90 |
| LncRNA | involved_in | biomarker | 0.90 |
| MYC | risk_factor_for | gene | 0.90 |
| Circadian Rhythm Disruption | contributes_to | phenotype | 0.90 |
| PI3K/AKT/mTOR Pathway Alterations | contributes_to | mechanism | 0.90 |
| Cgas/Sting Signaling | involved_in | pathway | 0.88 |
| AIMP2-DX2 | causes | protein | 0.85 |
| cGAS/STING | modulates | pathway | 0.85 |
| MYC | promotes | gene | 0.82 |
| cGAS/STING Pathway Deregulation | associated_with | mechanism | 0.80 |
| P53 | regulates | protein | 0.80 |
| AUTOPHAGY | promotes | process | 0.80 |
| Ferroptosis | promotes | process | 0.75 |
| AUTOPHAGY | involved_in | process | 0.70 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||