Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about cGAS/STING: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| type I interferon | activates | process | 0.95 |
| antitumor T cell responses | promotes | process | 0.95 |
| Cytosolic DNA | associated_with | compound | 0.95 |
| Innate Immune Response | involved_in | process | 0.95 |
| Cellular Senescence | regulates | process | 0.95 |
| Oncogenesis | contributes_to | disease | 0.90 |
| ALS | involved_in | disease | 0.90 |
| Cancer Development | modulates | process | 0.85 |
| Cancer Suppression | mediates | process | 0.85 |
| Source | Relation | Type | Str |
|---|---|---|---|
| endogenous DNA | activates | process | 0.90 |
| mitochondrial DNA | activates | compound | 0.90 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
neurodegeneration | 2026-04-08 | 0 hypotheses
neuroinflammation | 2026-04-07 | 0 hypotheses
neurodegeneration | 2026-04-07 | 0 hypotheses
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||