concept

LNCRNA

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about LNCRNA: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

299Connections

0Hypotheses

3Analyses

50Outgoing

50Incoming

No summary available yet. View on Wiki →

💡 Concept Info

Name	LNCRNA
Related Diseases	Cancer Initiation, Cancer Metastasis, Cardiovascular, Inflammation, Tumor

Wiki Pages (20)

Knowledge base pages for this entity

Pathway Diagram

graph TD
    LNCRNA["LNCRNA"]
    style LNCRNA fill:#1a237e,stroke:#4fc3f7,stroke-width:3px
    LNCRNA -->|"involved_in"| Cancer_Initiation["Cancer Initiation"]
    LNCRNA -->|"involved_in"| Cancer_Development["Cancer Development"]
    LNCRNA -->|"regulates"| Chromatin_Organization["Chromatin Organization"]
    LNCRNA -->|"regulates"| Transcriptional_Regulation["Transcriptional Regulation"]
    LNCRNA -->|"regulates"| Post_transcriptional_Regulatio["Post-transcriptional Regulation"]
    LNCRNA -->|"contributes to"| Tumor_Initiation["Tumor Initiation"]
    LNCRNA -->|"contributes to"| Tumor_Growth["Tumor Growth"]
    LNCRNA -->|"contributes to"| Metastasis["Metastasis"]
    INFLAMMATION([INFLAMMATION]) -->|"activates"| LNCRNA
    GAP43([GAP43]) -->|"activates"| LNCRNA
    RNA([RNA]) -->|"activates"| LNCRNA
    AND([AND]) -->|"activates"| LNCRNA
    LOC100911717([LOC100911717]) -->|"activates"| LNCRNA
    DNA([DNA]) -->|"regulates"| LNCRNA
    MIR31HG([MIR31HG]) -->|"activates"| LNCRNA
    HUNTINGTON([HUNTINGTON]) -->|"activates"| LNCRNA

Outgoing (200)

Target	Relation	Type	Str
Cancer Initiation	involved_in	disease	0.85
Chromatin Organization	regulates	process	0.85
Transcriptional Regulation	regulates	process	0.85
Cancer Metastasis	involved_in	disease	0.80
Cardiovascular	regulates	disease	0.65
Inflammation	activates	disease	0.65
Tumor	regulates	disease	0.65
Cancer	associated_with	disease	0.65
ALS	regulates	disease	0.65
Cancer	activates	disease	0.65
Senescence	activates	disease	0.65
Als	regulates	disease	0.65
Alzheimer	activates	disease	0.65
Huntington	activates	disease	0.65
Als	activates	disease	0.65
Amyotrophic Lateral Sclerosis	activates	disease	0.65
Parkinson	activates	disease	0.65
Pyroptosis	associated_with	disease	0.65
Ferroptosis	associated_with	disease	0.65
Necroptosis	associated_with	disease	0.65
Als	therapeutic_target	disease	0.65
Neuroinflammation	activates	disease	0.65
Alzheimer	associated_with	disease	0.65
Ferroptosis	activates	disease	0.65
Cancer	inhibits	disease	0.65
Glioblastoma	inhibits	disease	0.65
Als	inhibits	disease	0.65
Alzheimer	expressed_in	disease	0.65
Als	expressed_in	disease	0.65
Neuroinflammation	associated_with	disease	0.65
Alzheimer	regulates	disease	0.65
ALS	associated_with	disease	0.65
Inflammation	associated_with	disease	0.65
Tumor	inhibits	disease	0.65
ALS	inhibits	disease	0.65
Tumor	expressed_in	disease	0.65
ALS	expressed_in	disease	0.65
Tumor	activates	disease	0.65
Pyroptosis	biomarker_for	disease	0.65
Necroptosis	biomarker_for	disease	0.65
Ferroptosis	biomarker_for	disease	0.65
Cancer	regulates	disease	0.65
Neurodegeneration	activates	disease	0.65
CANCER	associated_with	gene	0.60
MIR31HG	activates	gene	0.60
AND	activates	gene	0.60
P16	regulates	gene	0.60
RAF	activates	gene	0.60
CANCER	activates	gene	0.60
GAP43	activates	gene	0.60

Incoming (99)

Source	Relation	Type	Str
INFLAMMATION	activates	gene	0.60
GAP43	activates	gene	0.60
RNA	activates	gene	0.60
AND	activates	gene	0.60
LOC100911717	activates	gene	0.60
DNA	regulates	gene	0.60
RNA	regulates	gene	0.60
AND	regulates	gene	0.60
MIR31HG	activates	gene	0.60
HUNTINGTON	activates	gene	0.60
PYROPTOSIS	associated_with	gene	0.60
GJA1	therapeutic_target	gene	0.60
ALZHEIMER	associated_with	gene	0.60
SLC16A1-AS1	inhibits	gene	0.60
APOPTOSIS	expressed_in	gene	0.60
P2RX7	expressed_in	gene	0.60
HMOX1	expressed_in	gene	0.60
ZCWPW1	activates	gene	0.60
FERMT2	activates	gene	0.60
CELF1	activates	gene	0.60
FERROPTOSIS	activates	gene	0.60
ALZHEIMER	regulates	gene	0.60
DNA	activates	gene	0.60
AMYOTROPHIC LATERAL SCLEROSIS	activates	gene	0.60
PARKINSON	activates	gene	0.60
ALZHEIMER	activates	gene	0.60
HUNTINGTIN	activates	gene	0.60
HUNTINGTON'S DISEASE	activates	gene	0.60
ALZHEIMER'S DISEASE	activates	gene	0.60
NEURODEGENERATIVE DISEASES	regulates	gene	0.60
MIRNAS	associated_with	gene	0.60
INFLAMMATION	associated_with	gene	0.60
AUTOPHAGY	associated_with	gene	0.60
AND	associated_with	gene	0.60
FERROPTOSIS	associated_with	gene	0.60
NEUROINFLAMMATION	activates	gene	0.60
NEUROTOXICITY	activates	gene	0.60
ROS	activates	gene	0.60
SRPK1	activates	gene	0.60
GJA1	associated_with	gene	0.60
GENES	associated_with	gene	0.60
ALZHEIMER'S DISEASE	associated_with	gene	0.60
FOSL2	activates	gene	0.60
GSH	activates	gene	0.60
NAMPT	activates	gene	0.60
GBM	interacts_with	gene	0.60
APOPTOSIS	inhibits	gene	0.60
RNA	interacts_with	gene	0.60
MIR-1269	interacts_with	gene	0.60
AND	inhibits	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (3)

Scientific analyses that reference this entity

What are the conserved secondary structures in dilncRNAs that enable selective t

molecular biology | 2026-04-10 | 0 hypotheses

What determines the specificity of DDR protein recruitment to dilncRNA-induced c

neurodegeneration | 2026-04-08 | 0 hypotheses

How do dilncRNAs specifically drive molecular crowding and phase separation of D

neurodegeneration | 2026-04-08 | 0 hypotheses

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

LNCRNA

Understanding Entity Pages

Wiki Pages (20)

Epigenetic Dysregulation in Neurodegeneration

Epigenetic Dysregulation Comparison -- AD/PD/ALS/FTD/HD

Epigenetic Alterations in Alzheimer's Disease

NPAS3 Gene

RNA Metabolism Dysregulation in Alzheimer's Disease

FOXO1 Protein

Transcriptional Regulation in Neurodegeneration

CNTF Signaling Pathway in Neurodegeneration

RICTOR Protein

Epigenetic Mechanisms in Alzheimer's Disease

Neuroinflammation in Parkinson's Disease

rgs9

EPHA6 — Ephrin Type-A Receptor 6

Extracellular Vesicles in Neurodegeneration

MSA Genetics and Risk Factors

RNA-Targeted Therapies in Neurodegeneration

TBX2 — T-Box Transcription Factor 2

epigenetics-neurodegeneration

EPHA8 Gene

Epigenetic Changes in PSP