protein

HNF4APROTEIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about HNF4APROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Hepatocyte Nuclear Factor 4 Alpha (HNF4A, also called HNF4α) is a ligand-activated transcription factor and member of the nuclear receptor superfamily[@lau2020].

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🔬 Protein Info

Gene Symbol	HNF4APROTEIN
Chromosome	20q13.12
Protein Type	Transcription Factor
Function	is a ligand-activated transcription factor and member of the nuclear receptor superfamily[@lau2020].
Primary Expression	liver, pancreas, kidney
Subcellular Localization	</strong></td><td>Nucleus</td></tr>
Molecular Weight	52 kDa
GeneCards	HNF4APROTEIN
Human Protein Atlas	HNF4APROTEIN
Associated Diseases	Hepatitis
Interactions	AKT, AKT1, AND, AXIN1, CANCER, CCND1
KG Connections	97 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

Hepatocyte Nuclear Factor 4 Alpha

protein · 1247 words

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Pathway Diagram

graph TD
    HNF4APROTEIN["HNF4APROTEIN"]
    neurodegeneration["neurodegeneration"]
    HNF4APROTEIN -->|"implicated_in"| neurodegeneration
    style HNF4APROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning HNF4APROTEIN in their description or question text

No additional research found