gene

IQCK

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about IQCK: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

7Connections

0Hypotheses

0Analyses

5Outgoing

2Incoming

Summary

IQCK — IQ Motif Containing Kinase

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🧬 Gene Info

Gene Symbol	IQCK
Full Name	IQ Motif Containing Kinase
Protein Type	Kinase
Function	IQCK is a serine/threonine protein kinase with an IQ motif that may mediate calmodulin binding.
Primary Expression	brain tissue, particularly in regions affected by Alzheimer's disease pathology
GeneCards	IQCK
Human Protein Atlas	IQCK
Associated Diseases	Alzheimer's Disease
KG Connections	7 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

IQCK — IQ Motif Containing Kinase

gene · 522 words

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Genes

index · 271 words

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Pathway Diagram

flowchart TD
    IQCK(["IQCK"])
    Alzheimer_s_Disease["Alzheimer's Disease"]
    Amyloid_beta(["Amyloid-beta"])
    Tau(["Tau"])
    Neuroinflammation("Neuroinflammation")
    Synaptic_Dysfunction("Synaptic Dysfunction")
    neurodegeneration["neurodegeneration"]

    IQCK -->|"associated with"| Alzheimer_s_Disease
    IQCK -->|"associated with"| Amyloid_beta
    IQCK -->|"associated with"| Tau
    IQCK -->|"associated with"| Neuroinflammation
    IQCK -->|"associated with"| Synaptic_Dysfunction
    IQCK -->|"implicated in"| neurodegeneration

    style IQCK fill:#1a237e,stroke:#4fc3f7,stroke-width:3px,color:#fff

Outgoing (5)

Target	Relation	Type	Str
Alzheimer's Disease	associated_with	disease	0.80
Amyloid-beta	associated_with	protein	0.70
Synaptic Dysfunction	associated_with	biological_process	0.70
Tau	associated_with	protein	0.70
Alzheimer's disease	implicated_in	disease	0.60

Incoming (2)

Source	Relation	Type	Str
CD2AP	implicated_in	gene	0.60
EPHA1	implicated_in	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found