Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about ITGA5: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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graph TD
ITGA5["ITGA5"]
ITGA5 -->|"upregulates"| Papillary_Renal_Cell_Carcinoma["Papillary Renal Cell Carcinoma"]
ITGA5 -->|"target for"| Ms["Ms"]
ITGA5 -->|"target for"| Macular_Degeneration["Macular Degeneration"]
ITGA5 -->|"target for"| Alzheimer["Alzheimer"]
ITGA5 -->|"target for"| ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"]
ITGA5 -->|"target for"| MMP2["MMP2"]
ITGA5 -->|"target for"| Nf__b["Nf-Kappab"]
NF__B["NF-KappaB"] -->|"target for"| ITGA5
NEURODEGENERATIVE_DISORDERS["NEURODEGENERATIVE DISORDERS"] -->|"target for"| ITGA5
COL1A1["COL1A1"] -->|"target for"| ITGA5
MMP9["MMP9"] -->|"target for"| ITGA5
ALZHEIMER["ALZHEIMER"] -->|"target for"| ITGA5
AND["AND"] -->|"target for"| ITGA5
GENES["GENES"] -->|"target for"| ITGA5| Target | Relation | Type | Str |
|---|---|---|---|
| Papillary Renal Cell Carcinoma | upregulates | disease | 0.70 |
| Ms | therapeutic_target | disease | 0.65 |
| Macular Degeneration | therapeutic_target | disease | 0.65 |
| Alzheimer | therapeutic_target | disease | 0.65 |
| ALZHEIMER'S DISEASE | therapeutic_target | gene | 0.60 |
| MMP2 | therapeutic_target | gene | 0.60 |
| Nf-Κb | therapeutic_target | pathway | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity