Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about LEARNING: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| Synaptic Refinement | involved_in | process | 0.85 |
| Synaptic Autophagy | associated_with | process | 0.85 |
| Source | Relation | Type | Str |
|---|---|---|---|
| BDNF | promotes | gene | 0.90 |
| EXERCISE | activates | phenotype | 0.72 |
| BDNF | activates | protein | 0.68 |
| LTP | regulates | phenotype | 0.68 |
| M1_RECEPTOR | regulates | protein | 0.64 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| Neuroplasticity-Enhanced Learning Hypothesis | 0.424 | methodology | Unable to extract research questions - t |
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| Curcumin Improves Neurogenesis in Alzheimer's Disease Mice via the Upregulation [PMID:38791161] | Lou S, Gong D, Yang M, Qiu Q, Luo J et a | Int J Mol Sci | 2024 | 0 |
| A small TAT-TrkB peptide prevents BDNF receptor cleavage and restores synaptic p [PMID:39205389] | Fonseca-Gomes J, Costa-Coelho T, Ferreir | Mol Ther | 2024 | 0 |
| Efficacy of Probiotic Supplements on Brain-Derived Neurotrophic Factor, Inflamma [PMID:38201846] | Hsu YC, Huang YY, Tsai SY, Kuo YW, Lin J | Nutrients | 2023 | 0 |
| Brain-derived neurotrophic factor in Alzheimer's disease and its pharmaceutical [PMID:35090576] | Gao L, Zhang Y, Sterling K, Song W | Transl Neurodegener | 2022 | 0 |
| The role of CREB and BDNF in neurobiology and treatment of Alzheimer's disease. [PMID:32603820] | Amidfar M, de Oliveira J, Kucharska E, B | Life Sci | 2020 | 0 |
| Neurotrophic Factor BDNF, Physiological Functions and Therapeutic Potential in D [PMID:33096634] | Colucci-D'Amato L, Speranza L, Volpicell | Int J Mol Sci | 2020 | 0 |
| Lactate Mediates the Effects of Exercise on Learning and Memory through SIRT1-De [PMID:30692222] | El Hayek L, Khalifeh M, Zibara V, Abi As | J Neurosci | 2019 | 0 |
| Brain-derived neurotrophic factor. [PMID:15518235] | Binder DK, Scharfman HE | Growth Factors | 2004 | 0 |
| Exercise: a behavioral intervention to enhance brain health and plasticity. [PMID:12086747] | Cotman CW, Berchtold NC | Trends Neurosci | 2002 | 0 |
| Neurotrophins and depression. [PMID:10101965] | Altar CA | Trends Pharmacol Sci | 1999 | 0 |