IGF2

Understanding Entity Pages

This page aggregates everything SciDEX knows about IGF2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

IGF2 is a gene implicated in neurodegeneration research. Key relationships include: associated with, inhibits, activates. Associated with Aging, Als, Alzheimer. Connected to 64 entities in the SciDEX knowledge graph.

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graph TD
    IGF2["<b>IGF2</b>"]
    Synaptic_Plasticity(["Synaptic Plasticity"])
    IGF2 -->|"mediates"| Synaptic_Plasticity
    Memory["Memory"]
    IGF2 -->|"modulates"| Memory
    Alzheimer_s_Disease{"Alzheimer's Disease"}
    IGF2 -->|"associated with"| Alzheimer_s_Disease
    Parkinson_s_Disease{"Parkinson's Disease"}
    IGF2 -->|"associated with"| Parkinson_s_Disease
    Huntington_s_Disease{"Huntington's Disease"}
    IGF2 -->|"associated with"| Huntington_s_Disease
    Neurodevelopmental_Disorders{"Neurodevelopmental Disorders"}
    IGF2 -->|"treats"| Neurodevelopmental_Disorders
    synaptic_plasticity(["synaptic plasticity"])
    IGF2 -->|"regulates"| synaptic_plasticity
    learning_and_memory(["learning and memory"])
    IGF2 -->|"activates"| learning_and_memory
    amyotrophic_lateral_sclerosis{"amyotrophic lateral sclerosis"}
    IGF2 -->|"biomarker for"| amyotrophic_lateral_sclerosis
    IGF2R["IGF2R"]
    IGF2 -->|"interacts with"| IGF2R
    Alzheimer_s_disease{"Alzheimer's disease"}
    IGF2 -->|"associated with"| Alzheimer_s_disease
    Parkinson_s_disease{"Parkinson's disease"}
    IGF2 -->|"associated with"| Parkinson_s_disease
    JUN["JUN"]
    JUN -->|"expressed in"| IGF2
    MIRNAS["MIRNAS"]
    MIRNAS -->|"therapeutic target"| IGF2
    APOPTOSIS["APOPTOSIS"]
    APOPTOSIS -->|"therapeutic target"| IGF2
    MICRORNAS["MICRORNAS"]
    MICRORNAS -->|"therapeutic target"| IGF2
    RB1["RB1"]
    RB1 -->|"regulates"| IGF2
    IGF2R -->|"expressed in"| IGF2
    ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"]
    ALZHEIMER_S_DISEASE -->|"associated with"| IGF2
    ALZHEIMER["ALZHEIMER"]
    ALZHEIMER -->|"associated with"| IGF2
    style IGF2 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0