concept

LINC00599

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about LINC00599: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

35Connections

0Hypotheses

0Analyses

26Outgoing

9Incoming

No summary available yet. View on Wiki →

💡 Concept Info

Name	LINC00599
Key Genes/Proteins	G3BP1, MYH9
Related Diseases	Pulmonary Hypertension, Hypoxic Conditions, Hypoxic Pulmonary Hypertension, Hypoxia

Pathway Diagram

graph TD
    LINC00599["LINC00599"]
    LINC00599 -->|"promotes"| Pulmonary_Hypertension["Pulmonary Hypertension"]
    LINC00599 -->|"interacts"| G3BP1["G3BP1"]
    LINC00599 -->|"interacts"| MYH9["MYH9"]
    LINC00599 -->|"expressed in"| Pulmonary_Arterial_Smooth_Musc["Pulmonary Arterial Smooth Muscle Cells"]
    LINC00599 -->|"expressed in"| Pulmonary_Artery_Smooth_Muscle["Pulmonary Artery Smooth Muscle Cells"]
    LINC00599 -->|"involved_in"| Vascular_Remodeling["Vascular Remodeling"]
    Hypoxia["Hypoxia"] -->|"upregulates"| LINC00599
    G3BP1 -->|"interacts"| LINC00599
    MYH9 -->|"interacts"| LINC00599
    ZNF263["ZNF263"] -->|"regulates"| LINC00599
    RNA["RNA"] -->|"regulates"| LINC00599
    AND["AND"] -->|"activates"| LINC00599

Outgoing (26)

Target	Relation	Type	Str
Pulmonary Hypertension	associated_with	disease	0.95
Pulmonary Hypertension	promotes	disease	0.95
Hypoxic Conditions	upregulates	phenotype	0.92
G3BP1	interacts_with	protein	0.90
MYH9	interacts_with	protein	0.90
Pulmonary Arterial Smooth Muscle Cells	expressed_in	cell_type	0.90
Pulmonary Arterial Smooth Muscle Cell Proliferation	promotes	process	0.90
Pulmonary Artery Smooth Muscle Cells	expressed_in	cell_type	0.90
Pulmonary Artery Medial Layer	expressed_in	cell_type	0.90
Hypoxic Pulmonary Hypertension	treats	disease	0.90
Vascular Remodeling	involved_in	process	0.85
Pulmonary Arterial Smooth Muscle Cell Proliferation	modulates	process	0.85
Vascular Remodeling	modulates	process	0.85
Hypoxia	upregulates	phenotype	0.85
Stress Granule Formation	modulates	process	0.85
Ms	activates	disease	0.65
Cardiovascular	activates	disease	0.65
Hypertension	activates	disease	0.65
AND	activates	gene	0.60
MYH9	regulates	gene	0.60
Myosin	regulates	protein	0.60
G3BP1	activates	gene	0.60
Rb	activates	protein	0.60
MYH9	activates	gene	0.60
RNA	activates	gene	0.60
RNA	regulates	gene	0.60

Incoming (9)

Source	Relation	Type	Str
Hypoxia	upregulates	phenotype	0.90
G3BP1	interacts_with	protein	0.90
MYH9	interacts_with	gene	0.90
ZNF263	regulates	gene	0.85
G3BP1	activates	gene	0.60
MYH9	regulates	gene	0.60
RNA	regulates	gene	0.60
AND	activates	gene	0.60
ZNF263	activates	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found