concept

MAPK SIGNALING PATHWAY

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about MAPK SIGNALING PATHWAY: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

21Connections
0Hypotheses
0Analyses
10Outgoing
11Incoming

No summary available yet. View on Wiki →

💡 Concept Info
NameMAPK SIGNALING PATHWAY

Wiki Pages (20)

Knowledge base pages for this entity

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Pathway Diagram

graph TD
    MAPK_SIGNALING_PATHWAY["MAPK SIGNALING PATHWAY"]
    MAPK_SIGNALING_PATHWAY -->|"activates"| Pyroptosis["Pyroptosis"]
    MAPK_SIGNALING_PATHWAY -->|"activates"| Inflammation["Inflammation"]
    MAPK_SIGNALING_PATHWAY -->|"regulates"| Neuroinflammatory_Responses["Neuroinflammatory Responses"]
    MAPK_SIGNALING_PATHWAY -->|"mediates"| Neuroprotection["Neuroprotection"]
    MAPK_SIGNALING_PATHWAY -->|"involved_in"| EV_A71_Infection["EV-A71 Infection"]
    RAS["RAS"] -->|"upstream_of"| MAPK_SIGNALING_PATHWAY
    Berberine["Berberine"] -->|"inhibits"| MAPK_SIGNALING_PATHWAY
    DUSP1["DUSP1"] -->|"inhibits"| MAPK_SIGNALING_PATHWAY
    Naringenin["Naringenin"] -->|"inhibits"| MAPK_SIGNALING_PATHWAY
    Macluraparishin_C["Macluraparishin C"] -->|"activates"| MAPK_SIGNALING_PATHWAY
    berberine["berberine"] -->|"inhibits"| MAPK_SIGNALING_PATHWAY
    Yiqi_Tongluo_Granule["Yiqi Tongluo Granule"] -->|"regulates"| MAPK_SIGNALING_PATHWAY
    TP53["TP53"] -->|"interacts"| MAPK_SIGNALING_PATHWAY

Outgoing (10)

TargetRelationTypeStr
Tnf-Α/Nf-Κb/Mapk Signaling Pathwayinvolved_inpathway0.90
Neuroinflammatory Responsesregulatesprocess0.85
Colitis-Associated Colorectal Cancerassociated_withdisease0.85
Pyroptosisactivatesprocess0.85
Inflammationactivatesprocess0.85

Incoming (11)

SourceRelationTypeStr
Berberineinhibitscompound0.95
RASupstream_ofprotein0.95
Berberineinhibitscompound0.92
DUSP1inhibitsprotein0.90
Macluraparishin Cactivatescompound0.90

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found