MBNL2

Understanding Entity Pages

This page aggregates everything SciDEX knows about MBNL2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

Muscleblind-like 2 (MBNL2) is an RNA-binding protein that regulates alternative splicing in the brain, implicated in myotonic dystrophy, ALS, and Alzheimer's disease.

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flowchart TD
    N0["MBNL2"]
    N1["RNA"]
    N0 -->|"interacts with"| N1
    N2["DMPK"]
    N0 -->|"interacts with"| N2
    N3["MBNL1"]
    N0 -->|"interacts with"| N3
    N4["AND"]
    N0 -->|"interacts with"| N4
    N3 -->|"interacts with"| N0
    N1 -->|"interacts with"| N0
    N2 -->|"interacts with"| N0
    N5["Proteins"]
    N0 -->|"interacts with"| N5
    N6["neurodegeneration"]
    N0 -->|"implicated in"| N6

    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    class N1 gene
    class N2 gene
    class N3 gene
    class N4 gene
    class N5 protein