| Gene Symbol | MBNL2 |
| Function | Through these domains, MBNL2 binds to pre-mRNA and regulates the alternative splicing of numerous neuronal transcripts[@sinha2020]. |
| Ensembl ID | ENSG00000128591 |
| GeneCards | MBNL2 |
| Human Protein Atlas | MBNL2 |
| Neuronal nitric oxide synthase (nNOS) | Alternative splicing controlled by MBNL2 affects nitric oxide signaling |
| CLN3 and other neuronal transcripts | MBNL2 influences splicing of genes involved in lysosomal function |
| Cerebral cortex | particularly layer 2/3 pyramidal neurons |
| Hippocampus | CA1 region and dentate gyrus granule cells |
| Cerebellum | Purkinje cells and granule cell layer |
| Substantia nigra | dopaminergic neurons |
| Brainstem | various nuclei |
| Nucleus | where it performs splicing functions |
| Cytoplasm | associated with RNA granules |
| Synaptic compartments | present in dendritic spines |
| Associated Diseases | Alzheimer's disease, Parkinson's disease, ALS |
| Interactions | DMPK, MBNL1, Proteins, RNA |
| KG Connections | 10 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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