Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about MDA: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| AE | downregulates | compound | 0.80 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| Thalamocortical Synchrony Restoration via NMDA Modulation | 0.542 | neuroscience | Circuit-level neural dynamics in neurode |
| Cortico-Striatal Synchrony Restoration via NMDA Modulation | 0.500 | neuroscience | Circuit-level neural dynamics in neurode |
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| Inspired by molecular dynamic simulation, exploring chemical constituents of alc [PMID:40166865] | Shinge J, Muthal A, Walhekar V, Bagul C, | Journal of biomolecular struct | 2026 | 0 |
| Cognitive loss after brain trauma results from sex-specific activation of synapt [PMID:40796363] | Arizanovska D, Bush GF, Dallera CA, Folo | Brain | 2026 | 0 |
| Inhibition of GluN2B-containing N-methyl-D-aspartate receptors by radiprodil. [PMID:40994429] | Banke TG, Regan MC, Perszyk RE, Zhang L, | Brain | 2026 | 0 |
| GluN2B-specific NMDAR positive allosteric modulation reverses cognitive and beha [PMID:41512078] | Ge Y, Tian T, Li B, Axerio-Cillies P, Ch | Sci Adv | 2026 | 0 |
| Zipper-interacting Protein Kinase Modulates Gene Expression Linked to Synaptic a [PMID:41526727] | Mei Y, Zheng L, He M, Wang L, Zhou Y et | Mol Neurobiol | 2026 | 0 |
| Multi-biofluid metabolomics coupled with gene network reveals stage-specific alt [PMID:41534821] | Cadaxo AS, Cotrin JC, Valente AP, Lopes | Brain Res | 2026 | 0 |
| Aberrant mRNA splicing and impaired hippocampal neurogenesis in Grin2b mutant mi [PMID:41675057] | Farsi Z, Nicolella A, Simmons SK, Shin W | iScience | 2026 | 0 |
| From synapse to system: mechanistic pathways of neural signaling dysfunction in [PMID:41799440] | Gupta R, Jha NK, Kumar N, Nagraik R, Rav | Front Cell Dev Biol | 2026 | 0 |
| Cellular Prion Protein Engages the N-Methyl-d-Aspartate Receptor through N- and [PMID:41860118] | Mayfield JE, Wang J, Tovell H, Taylor SS | Biochemistry | 2026 | 0 |
| Multisession epidural direct current stimulation of the auditory cortex mitigate [PMID:41747412] | Fernández Del Campo IS, Cebrián-León A, | Hearing research | 2026 | 0 |