Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about AE: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| PI3K | activates | protein | 0.80 |
| AKT | activates | protein | 0.80 |
| MDA | downregulates | compound | 0.80 |
| LDH | downregulates | protein | 0.80 |
| Caspase 3 | downregulates | protein | 0.80 |
| SOD | upregulates | protein | 0.80 |
| Bcl-2 | upregulates | protein | 0.80 |
| Bax | downregulates | protein | 0.80 |
| Ischemic stroke | treats | disease | 0.80 |
| mTOR | activates | protein | 0.80 |
| NF-κB | inhibits | protein | 0.80 |
| TNF-α | downregulates | protein | 0.80 |
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
neuroinflammation | 2026-04-15 | 2 hypotheses Top: 0.605
neurodegeneration | 2026-04-11 | 0 hypotheses
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||