gene

MTERF1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about MTERF1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

6Connections

0Hypotheses

0Analyses

2Outgoing

4Incoming

0Experiments

0Debates

Summary

Page for MTERF1 Gene - Mitochondrial Transcription Termination Factor 1

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🧬 Gene Info

Gene Symbol	MTERF1
Full Name	Mitochondrial Transcription Termination Factor 1
Aliases	Page for MTERF1 Gene
Chromosome	7q21.3
Function	MTERF1 is a mitochondrial protein that regulates transcription of mitochondrial DNA (mtDNA)
Primary Expression	High in brain, heart, skeletal muscle (mitochondrial)
Amino Acids	399 aa
Exons	2
UniProt ID	P56183
NCBI Gene ID	5101
Ensembl ID	ENSG00000138442
OMIM	605350
GeneCards	MTERF1
Human Protein Atlas	MTERF1
Associated Diseases	Parkinson's Disease, Alzheimer's Disease, Mitochondrial Disorders
KG Connections	6 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: MTERF1 — AlphaFold P56183 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

MTERF1 Gene - Mitochondrial Transcription Termination Factor 1

gene · 700 words

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Pathway Diagram

graph TD
    MTERF1["MTERF1"]
    Als{"Als"}
    MTERF1 -->|"regulates"| Als
    Ms{"Ms"}
    MTERF1 -->|"regulates"| Ms
    neurodegeneration["neurodegeneration"]
    MTERF1 -->|"implicated in"| neurodegeneration
    REST["REST"]
    REST -->|"regulates"| MTERF1
    MTDNA["MTDNA"]
    MTDNA -->|"regulates"| MTERF1
    TFAM["TFAM"]
    TFAM -->|"regulates"| MTERF1
    MITOCHONDRIAL_DNA["MITOCHONDRIAL DNA"]
    MITOCHONDRIAL_DNA -->|"regulates"| MTERF1
    style MTERF1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (2)

Target	Relation	Type	Str
Als	regulates	disease	0.65
Ms	regulates	disease	0.65

Incoming (4)

Source	Relation	Type	Str
REST	regulates	gene	0.60
TFAM	regulates	gene	0.60
MTDNA	regulates	gene	0.60
MITOCHONDRIAL DNA	regulates	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning MTERF1 in their description or question text

No additional research found